Browsing Journal of Biomechanical Engineering by Issue Date
Now showing items 1-20 of 5166
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Anisotropic Mechanical Response of Bovine Pericardium Membrane Through Bulge Test and In-Situ Confocal-Laser Scanning
(The American Society of Mechanical Engineers (ASME), 1/11/2023 )In this work, we present a new experimental setup for the assessment of the anisotropic properties of Bovine Pericardium (BP) membranes. The chemically fixed BP samples have been subjected to a bulge test with in situ ... -
Subcutaneous Drug Delivery: A Review of the State-of-the-Art Modeling and Experimental Techniques
(The American Society of Mechanical Engineers (ASME), 10/11/2022)Delivery of drug formulations through the subcutaneous route is a widely used modality for the treatment of several diseases, such as diabetes and auto-immune conditions. Subcutaneous injections are typically used to inject ... -
Optimizing the Porohyperelastic Response of a Layered Compliance Matched Vascular Graft to Promote Luminal Self-Cleaning
(The American Society of Mechanical Engineers (ASME), 10/6/2022 )Thrombosis and intimal hyperplasia have remained the major failure mechanisms of small-diameter vascular grafts used in bypass procedures. While most efforts to reduce thrombogenicity have used a biochemical surface ... -
Dynamic Deformation Calculation of Articular Cartilage and Cells Using Resonance-Driven Laser Scanning Microscopy
(The American Society of Mechanical Engineers (ASME), 10/6/2022 )The deformation of articular cartilage and its cells at the micro-scale during dynamic activities such as gait has high mechanoregulatory importance. Measuring the cellular geometries during such dynamics has been limited ... -
A Computational Study of Dynamic Obstruction in Type B Aortic Dissection
(The American Society of Mechanical Engineers (ASME), 12/21/2022)A serious complication in aortic dissection is dynamic obstruction of the true lumen (TL). Dynamic obstruction results in malperfusion, a blockage of blood flow to a vital organ. Clinical data reveal that increases in ... -
Stretch-Induced Uncrimping of Equatorial Sclera Collagen Bundles
(The American Society of Mechanical Engineers (ASME), 12/21/2022)Stretch-induced collagen uncrimping underlies the nonlinear mechanical behavior of the sclera according to what is often called the process of recruitment. We recently reported experimental measurements of sclera collagen ... -
Anatomical Characteristics Contributing to Patellar Dislocations Following MPFL Reconstruction: A Dynamic Simulation Study
(The American Society of Mechanical Engineers (ASME), 12/5/2022 )Pathologic anatomy is a primary factor contributing to redislocation of the patella following reconstruction of the medial patellofemoral ligament (MPFL). A pivot landing was simulated following MPFL reconstruction, with ... -
Impact of Blood Rheology on Transition to Turbulence and Wall Vibration Downstream of a Stenosis
(The American Society of Mechanical Engineers (ASME), 12/5/2022 )Previous experimental flow studies have demonstrated a delay (∼20%) in transition to turbulence for whole blood compared to a Newtonian analog fluid in both a straight pipe and eccentric stenosis model with ridged walls. ... -
Spatial and Temporal Mapping of Articular Cartilage Poro-Viscoelastic Material Properties Using Indentation
(The American Society of Mechanical Engineers (ASME), 12/9/2022 )Biphasic poro-viscoelastic constitutive material model (BPVE) captures both the fluid flow dependent and independent behavior of cartilage under stress relaxation type indentation. A finite element model based on BPVE ... -
Experimental Investigation of Dental Composites Degradation After Early Water Exposure
(The American Society of Mechanical Engineers (ASME), 12/9/2022 )While dental composite long-term aging has already been studied in the past, no data exist about the early aging while it might be detrimental regarding the composites' longevity. This study aims to better understand the ... -
Comparison of a Scaled Cadaver-Based Musculoskeletal Model With a Clinical Upper Extremity Model
(The American Society of Mechanical Engineers (ASME), 12/9/2022 )Reliably and accurately estimating joint/segmental kinematics from optical motion capture data has remained challenging. Studies objectively characterizing human movement patterns have typically involved inverse kinematics ... -
The Accelerated Transcatheter Heart Valve Testing Environment: Loading, Motion, and Fluid Dynamics
(The American Society of Mechanical Engineers (ASME), 12/9/2022 )Transcatheter aortic valve replacements (TAVRs) are an increasingly common treatment for aortic valve disease due to their minimally invasive delivery. As TAVR designs require thinner leaflets to facilitate catheter-based ... -
Biot Theory-Based Finite Element Modeling of Continuous Ultrasound Propagation Through Microscale Articular Cartilage
(The American Society of Mechanical Engineers (ASME), 12/9/2022 )Low-intensity ultrasound has shown promise in promoting the healing and regeneration of articular cartilage degraded by osteoarthritis. In this study, a two-dimensional finite element method (FEM) model was developed for ... -
Fluid Stresses in the Vicinity of Disk, Ball, and Tilting Disk Prosthetic Heart Valves From In-Vitro Measurements
(The American Society of Mechanical Engineers (ASME), 1977)Experiments were conducted in a steady flow test apparatus with an axisymmetric aortic shaped test chamber using hot-wire anemometry to obtain local momentum transfer and turbulence data in the ... -
Analysis of an Artificial Ventricle and Mock Circulatory System
(The American Society of Mechanical Engineers (ASME), 1977)A mathematical model is developed for calculating the pressures and flows in an artificial heart, its pneumatic drive unit, and a mock circulatory system. The system is divided into convenient ... -
A Motion Transducer for Use in the Intact In-Vitro Human Lumbar Spine
(The American Society of Mechanical Engineers (ASME), 1977)An electromechanical transducer was developed to enable measurement of the general six degree-of-freedom relative motion between lumbar vertebrae of the in-vitro human spine. The transducer system ... -
Comparison of Diastolic Ventricular Mechanics for Rigid Leaflet and Caged-Ball Prosthetic Valves
(The American Society of Mechanical Engineers (ASME), 1977)Computer model results are reported for the diastolic behavior of blood flow and muscle stress in the left ventricle of the heart. Comparisons are made between results for a rigid-leaflet ... -
Instrument Design for Vitreous Surgery via the Pars Plana
(The American Society of Mechanical Engineers (ASME), 1977)The vitreous body is a transparent gel occupying the posterior segment of the ocular globe. In diseased states, vision is obscured by haemorrhage or opacity or may be lost because of retinal ... -
Feasibility of an Active Control Scheme for Above Knee Prostheses
(The American Society of Mechanical Engineers (ASME), 1977)The level walking process for an above knee (A/K ) amputee with a conventional prosthesis greatly compromises the amputee’s mobility. The fact that conventional prostheses lock in hyperextension ... -
The Concentration Polarization Effect in Frozen Erythrocytes
(The American Society of Mechanical Engineers (ASME), 1977)An ideal, hydrated, nondilute pseudo-binary solution model is presented to describe the concentration polarization of solutes within cells during osmotic experiments. This model has been applied ...