Journal of Biomechanical Engineering: Recent submissions
Now showing items 801-820 of 5302
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An Automated Kinematic Measurement System for Sagittal Plane Murine Head Impacts
(The American Society of Mechanical Engineers (ASME), 2020)Mild traumatic brain injuries are typically caused by nonpenetrating head impacts that accelerate the skull and result in deformation of the brain within the skull. The shear and compressive strains caused by these ... -
Recovery of Tractions Exerted by Single Cells in Three-Dimensional Nonlinear Matrices
(The American Society of Mechanical Engineers (ASME), 2020)Cell-generated tractions play an important role in various physiological and pathological processes such as stem-cell differentiation, cell migration, wound healing, and cancer metastasis. Traction force microscopy (TFM) ... -
Short- and Long-Term Exercise Results in a Differential Achilles Tendon Mechanical Response
(The American Society of Mechanical Engineers (ASME), 2020)The study was conducted to define the biomechanical response of rat Achilles tendon after a single bout of exercise and a short or long duration of daily exercise. We hypothesized that a single bout or a short duration of ... -
Trueness of Fit of Biphasic Transversely Isotropic Parameters Model in the Porcine Temporomandibular Joint Disc and Mandibular Condylar Cartilage and Regional Dependence
(The American Society of Mechanical Engineers (ASME), 2020)Temporomandibular joint (TMJ) disorders (TMDs) are not well understood and the mechanical differences between the regions of the mandibular condylar cartilage (MCC) and the TMJ disc have not been thoroughly compared. As ... -
Cartilage Biomechanical Response Differs Under Physiological Biaxial Loads and Uniaxial Cyclic Compression
(The American Society of Mechanical Engineers (ASME), 2020)The main function of articular cartilage is to distribute loads and provide low friction for the opposing surfaces in synovial joints. Biphasic lubrication provided by high fluid load support due to relative motion of the ... -
Three-Dimensional Inflation Response of Porcine Optic Nerve Head Using High-Frequency Ultrasound Elastography
(The American Society of Mechanical Engineers (ASME), 2020)Characterization of the biomechanical behavior of the optic nerve head (ONH) in response to intraocular pressure (IOP) elevation is important for understanding glaucoma susceptibility. In this study, we aimed to develop ... -
Optical Coherence Tomography-Based Modeling of Stent Deployment in Heavily Calcified Coronary Lesion
(The American Society of Mechanical Engineers (ASME), 2020)In this work, a heavily calcified coronary artery model was reconstructed from optical coherence tomography (OCT) images to investigate the impact of calcification characteristics on stenting outcomes. The calcification ... -
Simulation of Brain Response to Noncontact Impacts Using Coupled Eulerian–Lagrangian Method
(The American Society of Mechanical Engineers (ASME), 2020)Finite element (FE) method has been widely used for gaining insights into the mechanical response of brain tissue during impacts. In this study, a coupled Eulerian−Lagrangian (CEL) formulation is implemented in impact ... -
Shear Wave Propagation and Estimation of Material Parameters in a Nonlinear, Fibrous Material
(The American Society of Mechanical Engineers (ASME), 2020)This paper describes the propagation of shear waves in a Holzapfel–Gasser–Ogden (HGO) material and investigates the potential of magnetic resonance elastography (MRE) for estimating parameters of the HGO material model ... -
MicroRNA-29a Involvement in Phenotypic Transformation of Venous Smooth Muscle Cells Via Ten–Eleven Translocation Methylcytosinedioxygenase 1 in Response to Mechanical Cyclic Stretch
(The American Society of Mechanical Engineers (ASME), 2020)Mechanical stimuli play an important role in vein graft restenosis and the abnormal migration and proliferation of vascular smooth muscle cells (VSMCs) are pathological processes contributing to this disorder. Here, based ... -
Personalized Fiber-Reinforcement Networks for Meniscus Reconstruction
(The American Society of Mechanical Engineers (ASME), 2020)The menisci are fibrocartilaginous tissues that are crucial to the load-sharing and stability of the knee, and when injured, these properties are compromised. Meniscus replacement scaffolds have utilized the circumferential ... -
Lumbar Spine Response of Computational Finite Element Models in Multidirectional Spaceflight Landing Conditions
(The American Society of Mechanical Engineers (ASME), 2020)The goals of this study are to compare the lumbar spine response variance between the hybrid III, test device for human occupant restraint (THOR), and global human body models consortium simplified 50th percentile (GHBMC ... -
On the Connection Between Geometry and Statically Determined Membrane Stresses in the Human Cornea
(The American Society of Mechanical Engineers (ASME), 2020)Under the action of the intraocular pressure (IOP), the human cornea is stressed and deforms acquiring a quasi-spherical configuration. If the stressed configuration is known, and the cornea is regarded as a membrane, ... -
Experimental Investigation of the Effect of Heart Rate on Flow in the Left Ventricle in Health and Disease—Aortic Valve Regurgitation
(The American Society of Mechanical Engineers (ASME), 2020)There is much debate in the literature surrounding the effects of heart rate on aortic regurgitation (AR). Despite the contradictory information, it is still widely believed that an increase in heart rate is beneficial due ... -
A Dynamic Escape Problem of Molecular Motors
(The American Society of Mechanical Engineers (ASME), 2020)Animal skeletal muscle exhibits very interesting behavior at near-stall forces (when the muscle is loaded so strongly that it can barely contract). Near this physical limit, the myosin II proteins may be unable to reach ... -
Biomechanical Comparison of a New Dynamic Ankle Orthosis to a Standard Ankle-Foot Orthosis During Walking
(The American Society of Mechanical Engineers (ASME), 2020)Patients who sustain irreversible cartilage damage or joint instability from ankle injuries are likely to develop ankle osteoarthritis (OA). A dynamic ankle orthosis (DAO) was recently designed with the intent to offload ... -
Infusion Jet Flow Control in Neonatal Double Lumen Cannulae
(The American Society of Mechanical Engineers (ASME), 2020)Clinical success of extracorporeal membrane oxygenation (ECMO) depends on the proper venous cannulation. Venovenous (VV) ECMO is the preferred clinical intervention as it provides a single-site access by utilizing a VV ... -
Clinical Contrast-Enhanced Computed Tomography With Semi-Automatic Segmentation Provides Feasible Input for Computational Models of the Knee Joint
(The American Society of Mechanical Engineers (ASME), 2020)Computational models can provide information on joint function and risk of tissue failure related to progression of osteoarthritis (OA). Currently, the joint geometries utilized in modeling are primarily obtained via manual ... -
Local Dynamic Stability of Self-Paced Treadmill Walking Versus Fixed-Speed Treadmill Walking
(The American Society of Mechanical Engineers (ASME), 2020)The purpose of this study was to assess the influence of gait stability induced by treadmill accelerations during self-paced treadmill walking (SPW). Local dynamic stability of three-dimensional (3D) upper body accelerations ... -
Density Variation in the Expanded Polystyrene Foam of Bicycle Helmets and Its Influence on Impact Performance
(The American Society of Mechanical Engineers (ASME), 2020)Bicycle helmets attenuate head impacts using expanded polystyrene (EPS) foam liners. The EPS density plays a key role in determining the helmet and head response during an impact. Prior pilot work in our lab showed that ...