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    Blood Freezing to Nearly Absolute Zero Temperature: −272.29°C

    Source: Journal of Biomechanical Engineering:;1981:;volume( 103 ):;issue: 001::page 24
    Author:
    E. G. Cravalho
    ,
    C. E. Huggins
    ,
    K. R. Diller
    ,
    W. W. Watson
    DOI: 10.1115/1.3138240
    Publisher: The American Society of Mechanical Engineers (ASME)
    Abstract: Human erythrocytes were collected in ACD anticoagulant, glycerolized with an equal volume of 8.6 M glycerol, 8 percent glucose, 1 percent fructose, and 0.3 percent Na2 EDTA solution, sealed in glass ampules, and frozen to −272.29°C (0.86°K) in liquid helium under high vacuum. Biological assays performed after thawing and three-stage dialysis to remove the glycerol showed less than 1 percent hemolysis. Intracellular potassium, 2,3 DPG, and ATP were within the normal range.
    keyword(s): Temperature , Freezing , Glass , Vacuum , Absolute zero , Assaying , Thawing , Blood , Helium , Potassium AND Erythrocytes ,
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      Blood Freezing to Nearly Absolute Zero Temperature: −272.29°C

    URI
    http://yetl.yabesh.ir/yetl1/handle/yetl/94309
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    • Journal of Biomechanical Engineering

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    contributor authorE. G. Cravalho
    contributor authorC. E. Huggins
    contributor authorK. R. Diller
    contributor authorW. W. Watson
    date accessioned2017-05-08T23:10:41Z
    date available2017-05-08T23:10:41Z
    date copyrightFebruary, 1981
    date issued1981
    identifier issn0148-0731
    identifier otherJBENDY-25673#24_1.pdf
    identifier urihttp://yetl.yabesh.ir/yetl/handle/yetl/94309
    description abstractHuman erythrocytes were collected in ACD anticoagulant, glycerolized with an equal volume of 8.6 M glycerol, 8 percent glucose, 1 percent fructose, and 0.3 percent Na2 EDTA solution, sealed in glass ampules, and frozen to −272.29°C (0.86°K) in liquid helium under high vacuum. Biological assays performed after thawing and three-stage dialysis to remove the glycerol showed less than 1 percent hemolysis. Intracellular potassium, 2,3 DPG, and ATP were within the normal range.
    publisherThe American Society of Mechanical Engineers (ASME)
    titleBlood Freezing to Nearly Absolute Zero Temperature: −272.29°C
    typeJournal Paper
    journal volume103
    journal issue1
    journal titleJournal of Biomechanical Engineering
    identifier doi10.1115/1.3138240
    journal fristpage24
    journal lastpage26
    identifier eissn1528-8951
    keywordsTemperature
    keywordsFreezing
    keywordsGlass
    keywordsVacuum
    keywordsAbsolute zero
    keywordsAssaying
    keywordsThawing
    keywordsBlood
    keywordsHelium
    keywordsPotassium AND Erythrocytes
    treeJournal of Biomechanical Engineering:;1981:;volume( 103 ):;issue: 001
    contenttypeFulltext
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