YaBeSH Engineering and Technology Library

    • Journals
    • PaperQuest
    • YSE Standards
    • YaBeSH
    • Login
    View Item 
    •   YE&T Library
    • ASME
    • Journal of Biomechanical Engineering
    • View Item
    •   YE&T Library
    • ASME
    • Journal of Biomechanical Engineering
    • View Item
    • All Fields
    • Source Title
    • Year
    • Publisher
    • Title
    • Subject
    • Author
    • DOI
    • ISBN
    Advanced Search
    JavaScript is disabled for your browser. Some features of this site may not work without it.

    Archive

    Surface Strains of Porcine Tricuspid Valve Septal Leaflets Measured in Ex Vivo Beating Hearts

    Source: Journal of Biomechanical Engineering:;2016:;volume( 138 ):;issue: 011::page 111006
    Author:
    Amini Khoiy, Keyvan
    ,
    Biswas, Dipankar
    ,
    Decker, Thomas N.
    ,
    Asgarian, Kourosh T.
    ,
    Loth, Francis
    ,
    Amini, Rouzbeh
    DOI: 10.1115/1.4034621
    Publisher: The American Society of Mechanical Engineers (ASME)
    Abstract: Quantification of the tricuspid valve (TV) leaflets mechanical strain is important in order to understand valve pathophysiology and to develop effective treatment strategies. Many of the traditional methods used to dynamically open and close the cardiac valves in vitro via flow simulators require valve dissection. Recent studies, however, have shown that restriction of the atrioventricular valve annuli could significantly change their in vivo deformation. For the first time, the porcine valve leaflets deformation was measured in a passive ex vivo beating heart without isolating and remounting the valve annuli. In particular, the right ventricular apexes of porcine hearts (n = 8) were connected to a pulse-duplicator pump that maintained a pulsatile flow from and to a reservoir connected to the right atrium and the pulmonary arteries. This pump provided a right ventricular pressure (RVP) waveform that closely matched physiological values, leading to opening and closure of the tricuspid and pulmonary valves (PVs). At the midsection of the valve leaflets, the peak areal strain was 9.8 ± 2.0% (mean±standard error). The peak strain was 5.6 ± 1.1% and 4.3 ± 1.0% in the circumferential and radial directions, respectively. Although the right ventricle was beating passively, the leaflet peak areal strains closely matched the values measured in other atrioventricular valves (i.e., the mitral valve (MV)) in vivo. This technique can be used to measure leaflet strains with and without the presence of valve lesions to help develop/evaluate treatment strategies to restore normal valve deformation.
    • Download: (2.732Mb)
    • Show Full MetaData Hide Full MetaData
    • Get RIS
    • Item Order
    • Go To Publisher
    • Price: 5000 Rial
    • Statistics

      Surface Strains of Porcine Tricuspid Valve Septal Leaflets Measured in Ex Vivo Beating Hearts

    URI
    http://yetl.yabesh.ir/yetl1/handle/yetl/4234820
    Collections
    • Journal of Biomechanical Engineering

    Show full item record

    contributor authorAmini Khoiy, Keyvan
    contributor authorBiswas, Dipankar
    contributor authorDecker, Thomas N.
    contributor authorAsgarian, Kourosh T.
    contributor authorLoth, Francis
    contributor authorAmini, Rouzbeh
    date accessioned2017-11-25T07:17:53Z
    date available2017-11-25T07:17:53Z
    date copyright2016/10/21
    date issued2016
    identifier issn0148-0731
    identifier otherbio_138_11_111006.pdf
    identifier urihttp://138.201.223.254:8080/yetl1/handle/yetl/4234820
    description abstractQuantification of the tricuspid valve (TV) leaflets mechanical strain is important in order to understand valve pathophysiology and to develop effective treatment strategies. Many of the traditional methods used to dynamically open and close the cardiac valves in vitro via flow simulators require valve dissection. Recent studies, however, have shown that restriction of the atrioventricular valve annuli could significantly change their in vivo deformation. For the first time, the porcine valve leaflets deformation was measured in a passive ex vivo beating heart without isolating and remounting the valve annuli. In particular, the right ventricular apexes of porcine hearts (n = 8) were connected to a pulse-duplicator pump that maintained a pulsatile flow from and to a reservoir connected to the right atrium and the pulmonary arteries. This pump provided a right ventricular pressure (RVP) waveform that closely matched physiological values, leading to opening and closure of the tricuspid and pulmonary valves (PVs). At the midsection of the valve leaflets, the peak areal strain was 9.8 ± 2.0% (mean±standard error). The peak strain was 5.6 ± 1.1% and 4.3 ± 1.0% in the circumferential and radial directions, respectively. Although the right ventricle was beating passively, the leaflet peak areal strains closely matched the values measured in other atrioventricular valves (i.e., the mitral valve (MV)) in vivo. This technique can be used to measure leaflet strains with and without the presence of valve lesions to help develop/evaluate treatment strategies to restore normal valve deformation.
    publisherThe American Society of Mechanical Engineers (ASME)
    titleSurface Strains of Porcine Tricuspid Valve Septal Leaflets Measured in Ex Vivo Beating Hearts
    typeJournal Paper
    journal volume138
    journal issue11
    journal titleJournal of Biomechanical Engineering
    identifier doi10.1115/1.4034621
    journal fristpage111006
    journal lastpage111006-9
    treeJournal of Biomechanical Engineering:;2016:;volume( 138 ):;issue: 011
    contenttypeFulltext
    DSpace software copyright © 2002-2015  DuraSpace
    نرم افزار کتابخانه دیجیتال "دی اسپیس" فارسی شده توسط یابش برای کتابخانه های ایرانی | تماس با یابش
    yabeshDSpacePersian
     
    DSpace software copyright © 2002-2015  DuraSpace
    نرم افزار کتابخانه دیجیتال "دی اسپیس" فارسی شده توسط یابش برای کتابخانه های ایرانی | تماس با یابش
    yabeshDSpacePersian