| contributor author | Kaynia, Narges | |
| contributor author | Soohoo, Elaine | |
| contributor author | Keaveny, Tony M. | |
| contributor author | Kazakia, Galateia J. | |
| date accessioned | 2017-05-09T01:14:58Z | |
| date available | 2017-05-09T01:14:58Z | |
| date issued | 2015 | |
| identifier issn | 0148-0731 | |
| identifier other | bio_137_01_011010.pdf | |
| identifier uri | http://yetl.yabesh.ir/yetl/handle/yetl/157055 | |
| description abstract | This study investigated the effects of intraspecimen variations in tissue mineral density (TMD) on the apparentlevel stiffness of human trabecular bone. Highresolution finite element (FE) models were created for each of 12 human trabecular bone specimens, using both microcomputed tomography (خ¼CT) and “goldstandard†synchrotron radiation خ¼CT (SRخ¼CT) data. Our results confirm that incorporating TMD spatial variation reduces the calculated apparent stiffness compared to homogeneous TMD models. This effect exists for both خ¼CTand SRخ¼CTbased FE models, but is exaggerated in خ¼CTbased models. This study provides a direct comparison of خ¼CT to SRخ¼CT data and is thereby able to conclude that the influence of including TMD heterogeneity is overestimated in خ¼CTbased models. | |
| publisher | The American Society of Mechanical Engineers (ASME) | |
| title | Effect of Intraspecimen Spatial Variation in Tissue Mineral Density on the Apparent Stiffness of Trabecular Bone | |
| type | Journal Paper | |
| journal volume | 137 | |
| journal issue | 1 | |
| journal title | Journal of Biomechanical Engineering | |
| identifier doi | 10.1115/1.4029178 | |
| journal fristpage | 11010 | |
| journal lastpage | 11010 | |
| identifier eissn | 1528-8951 | |
| tree | Journal of Biomechanical Engineering:;2015:;volume( 137 ):;issue: 001 | |
| contenttype | Fulltext | |