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contributor authorKaynia, Narges
contributor authorSoohoo, Elaine
contributor authorKeaveny, Tony M.
contributor authorKazakia, Galateia J.
date accessioned2017-05-09T01:14:58Z
date available2017-05-09T01:14:58Z
date issued2015
identifier issn0148-0731
identifier otherbio_137_01_011010.pdf
identifier urihttp://yetl.yabesh.ir/yetl/handle/yetl/157055
description abstractThis study investigated the effects of intraspecimen variations in tissue mineral density (TMD) on the apparentlevel stiffness of human trabecular bone. Highresolution finite element (FE) models were created for each of 12 human trabecular bone specimens, using both microcomputed tomography (خ¼CT) and “goldstandardâ€‌ synchrotron radiation خ¼CT (SRخ¼CT) data. Our results confirm that incorporating TMD spatial variation reduces the calculated apparent stiffness compared to homogeneous TMD models. This effect exists for both خ¼CTand SRخ¼CTbased FE models, but is exaggerated in خ¼CTbased models. This study provides a direct comparison of خ¼CT to SRخ¼CT data and is thereby able to conclude that the influence of including TMD heterogeneity is overestimated in خ¼CTbased models.
publisherThe American Society of Mechanical Engineers (ASME)
titleEffect of Intraspecimen Spatial Variation in Tissue Mineral Density on the Apparent Stiffness of Trabecular Bone
typeJournal Paper
journal volume137
journal issue1
journal titleJournal of Biomechanical Engineering
identifier doi10.1115/1.4029178
journal fristpage11010
journal lastpage11010
identifier eissn1528-8951
treeJournal of Biomechanical Engineering:;2015:;volume( 137 ):;issue: 001
contenttypeFulltext


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