contributor author | Alexander A. Spector | |
contributor author | Panos G. Charalambides | |
contributor author | Aleksander S. Popel | |
contributor author | Mohammed Ameen | |
date accessioned | 2017-05-09T00:06:52Z | |
date available | 2017-05-09T00:06:52Z | |
date copyright | April, 2002 | |
date issued | 2002 | |
identifier issn | 0148-0731 | |
identifier other | JBENDY-26237#180_1.pdf | |
identifier uri | http://yetl.yabesh.ir/yetl/handle/yetl/126404 | |
description abstract | We consider the mechanical properties of the outer hair cell cytoskeleton. The cytoskeleton is represented as a set of microdomains of different sizes and orientations composed of actin filaments and spectrin crosslinks. An intermediate material between domains is also introduced. The domain characteristics are randomly generated and the histograms of the cytoskeleton stiffness moduli are obtained. We solve an inverse problem and estimate the stiffness of the crosslink and connective molecule in the intermediate material. We discovered a pattern of highly inhomogeneous deformation of the cytoskeleton where the circumferential strain is primarily determined by the deformation of the intermediate material. | |
publisher | The American Society of Mechanical Engineers (ASME) | |
title | Nanostructure, Effective Properties, and Deformation Pattern of the Cochlear Outer Hair Cell Cytoskeleton | |
type | Journal Paper | |
journal volume | 124 | |
journal issue | 2 | |
journal title | Journal of Biomechanical Engineering | |
identifier doi | 10.1115/1.1448521 | |
journal fristpage | 180 | |
journal lastpage | 187 | |
identifier eissn | 1528-8951 | |
keywords | Deformation | |
keywords | Stiffness | |
keywords | Membranes | |
keywords | Shear (Mechanics) | |
keywords | Stress AND Anisotropy | |
tree | Journal of Biomechanical Engineering:;2002:;volume( 124 ):;issue: 002 | |
contenttype | Fulltext | |