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contributor authorAlexander A. Spector
contributor authorPanos G. Charalambides
contributor authorAleksander S. Popel
contributor authorMohammed Ameen
date accessioned2017-05-09T00:06:52Z
date available2017-05-09T00:06:52Z
date copyrightApril, 2002
date issued2002
identifier issn0148-0731
identifier otherJBENDY-26237#180_1.pdf
identifier urihttp://yetl.yabesh.ir/yetl/handle/yetl/126404
description abstractWe consider the mechanical properties of the outer hair cell cytoskeleton. The cytoskeleton is represented as a set of microdomains of different sizes and orientations composed of actin filaments and spectrin crosslinks. An intermediate material between domains is also introduced. The domain characteristics are randomly generated and the histograms of the cytoskeleton stiffness moduli are obtained. We solve an inverse problem and estimate the stiffness of the crosslink and connective molecule in the intermediate material. We discovered a pattern of highly inhomogeneous deformation of the cytoskeleton where the circumferential strain is primarily determined by the deformation of the intermediate material.
publisherThe American Society of Mechanical Engineers (ASME)
titleNanostructure, Effective Properties, and Deformation Pattern of the Cochlear Outer Hair Cell Cytoskeleton
typeJournal Paper
journal volume124
journal issue2
journal titleJournal of Biomechanical Engineering
identifier doi10.1115/1.1448521
journal fristpage180
journal lastpage187
identifier eissn1528-8951
keywordsDeformation
keywordsStiffness
keywordsMembranes
keywordsShear (Mechanics)
keywordsStress AND Anisotropy
treeJournal of Biomechanical Engineering:;2002:;volume( 124 ):;issue: 002
contenttypeFulltext


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