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Effectiveness, Active Energy Produced by Molecular Motors, and Nonlinear Capacitance of the Cochlear Outer Hair Cell
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: Cochlear outer hair cells are crucial for active hearing. These cells have a unique form of motility, named electromotility, whose main features are the cell’s length changes, active force ...
Modes and Balance of Energy in the Piezoelectric Cochlear Outer Hair Cell Wall
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: Here, we analyze energy transformations in the outer hair cell and its effectiveness as a piezoelectric-type actuator in the cochlea. The major modes of energy are introduced, and a method to ...
Finite-Element Analysis of the Adhesion-Cytoskeleton-Nucleus Mechanotransduction Pathway During Endothelial Cell Rounding: Axisymmetric Model
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: Endothelial cells possess a mechanical network connecting adhesions on the basal surface, the cytoskeleton, and the nucleus. Transmission of force at adhesions via this pathway can deform the ...
Nanostructure, Effective Properties, and Deformation Pattern of the Cochlear Outer Hair Cell Cytoskeleton
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: We consider the mechanical properties of the outer hair cell cytoskeleton. The cytoskeleton is represented as a set of microdomains of different sizes and orientations composed of actin filaments ...
Characterization of the Nuclear Deformation Caused by Changes in Endothelial Cell Shape
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: We investigated the mechanotransduction pathway in endothelial cells between their nucleus and adhesions to the extracellular matrix. First, we measured nuclear deformations in response to alterations ...
Modeling the Mechanics of Tethers Pulled From the Cochlear Outer Hair Cell Membrane
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: Cell membrane tethers are formed naturally (e.g., in leukocyte rolling) and experimentally to probe membrane properties. In cochlear outer hair cells, the plasma membrane is part of the trilayer ...