Journal of Medical Devices: Recent submissions
Now showing items 481-500 of 1736
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Investigating the Mechanical Properties of Biological Brain Cells With Atomic Force Microscopy
(The American Society of Mechanical Engineers (ASME), 2018)Characterization of cell mechanical properties plays an important role in disease diagnoses and treatments. This paper uses advanced atomic force microscopy (AFM) to measure the geometrical and mechanical properties of two ... -
An Inertia-Deformability Hybrid Circulating Tumor Cell Chip: Design, Clinical Test, and Numerical Analysis
(The American Society of Mechanical Engineers (ASME), 2018)Detection and capture of circulating tumor cells (CTCs) with microfluidic chips hold significance in cancer prognosis, diagnosis, and anti-cancer treatment. The counting of CTCs provides potential tools to evaluate cancer ... -
A Practical Measurement of Parkinson's Patients Gait Using Simple Walker-Based Motion Sensing and Data Analysis
(The American Society of Mechanical Engineers (ASME), 2018)We present personal aid for mobility and monitoring (PAMM II), an instrumented walker for Parkinson's disease (PD) patients' gait monitoring. The objective of the walker is to aid in the diagnosis and monitoring of PD ... -
A Precision System for Computed Tomography-Guided Needle Placement in the Thorax and Abdomen—Technical Design and Performance Analysis
(The American Society of Mechanical Engineers (ASME), 2018)A system was developed for computed tomography (CT)-guided needle placement in the thorax and abdomen, providing precise aiming of a needle guide (NG) to reach a user-specified target in a single manual insertion. The ... -
Surface and Thermal Characteristics of Single-Use Electrosurgical Pencils After Clinical Reuse and In-Hospital Reprocessing
(The American Society of Mechanical Engineers (ASME), 2017)Safety and efficacy issues are associated with reprocessing of single-use electrosurgical pencils (EPs), requiring methods for assessing the reprocessing protocol before clinical reuse. This study aimed at monitoring the ... -
Design and Evaluation of a Robotic Device for Automated Tail Vein Cannulations in Rodent Models
(The American Society of Mechanical Engineers (ASME), 2017)Preclinical testing in rodent models is a ubiquitous part of modern biomedical research and commonly involves accessing the venous bloodstream for blood sampling and drug delivery. Manual tail vein cannulation is a ... -
Design of an Open-Source Binary Micromultileaf Collimator for a Small Animal Microradiotherapy System
(The American Society of Mechanical Engineers (ASME), 2017)Intensity modulated radiation therapy (IMRT) is performed on a regular basis in the clinic to create complex radiation fields to treat cancer, but it has not been implemented in microradiotherapy (mRT) for preclinical ... -
Design of a Novel, Adjustable Flow Rate, Reusable, Electricity-Free, Low-Cost Syringe Infusion Pump
(The American Society of Mechanical Engineers (ASME), 2017)We present a proof-of-concept design and preliminary data to demonstrate a novel syringe infusion pump that is low cost, nonelectric, reusable, and adjustable. This device addresses the need for infusion therapy in low- ... -
Design, Development, and Validation of an Intra-Osseous Needle Placement Guide
(The American Society of Mechanical Engineers (ASME), 2017)Intra-osseous (IO) needles are an easy and reliable alternative to intravenous (IV) access in the prehospital and emergency settings for treating patients in shock. The advantage of utilizing an IO is that secure, ... -
Review of Kinematics for Minimally Invasive Surgery and Tele-Echography Robots
(The American Society of Mechanical Engineers (ASME), 2017)This paper deals with the survey of kinematic structures adapted to specific medical robots: minimally invasive surgery (MIS) and tele-echography. The large diversity of kinematic architectures that can be found in medical ... -
Replication and Substitution of Anatomic Stabilizing Mechanisms in a Total Knee Design
(The American Society of Mechanical Engineers (ASME), 2017)While the majority of the total knees used today are of the cruciate retaining (CR) and cruciate substituting (PS) types, the results are not ideal in terms of satisfaction, function, and biomechanical parameters. It is ... -
A Proximally-Adjustable Variable Length Intramedullary Nail: Ex Vivo Quasi-Static and Cyclic Loading Evaluation
(The American Society of Mechanical Engineers (ASME), 2017)An adjustable-length intramedullary (IM) nail may reduce both complications secondary to fracture fixation and manufacturing costs. We hypothesized that our novel nail would have suitable mechanical performance. To test ... -
Design and Fabrication of a Low-Cost Three-Dimensional Bioprinter
(The American Society of Mechanical Engineers (ASME), 2017)Three-dimensional (3D) bioprinting offers innovative research vectors for tissue engineering. However, commercially available bioprinting platforms can be cost prohibitive to small research facilities, especially in an ... -
A Shape Memory Alloy-Based Compression Therapy Prototype Tested With Individuals in Seated Position
(The American Society of Mechanical Engineers (ASME), 2017)Orthostatic intolerance in patients can occur secondary to concomitant venous pooling and enhanced capillary filtration when standing upright, and is one of the principle causes of syncope or fainting. Compression therapy ... -
Pop-Up MEMS One-Way Endobronchial Valve for Treatment of Chronic Obstructive Pulmonary Disease
(The American Society of Mechanical Engineers (ASME), 2017)Chronic obstructive pulmonary disease (COPD) is the fourth leading cause of morbidity in aging populations worldwide. One of the most debilitating effects of COPD is hyperinflation, which restricts the function of healthier ... -
Assessing the Importance of Surgeon Hand Anthropometry on the Design of Medical Devices
(The American Society of Mechanical Engineers (ASME), 2017)Improperly designed medical devices can induce unwanted biomechanical stressors on their users, impacting health and career longevity. Despite this, manufacturers struggle to balance device design with the growing female ... -
Assessment of the Accuracy of Optical Shape Sensing for Needle Tracking Interventions
(The American Society of Mechanical Engineers (ASME), 2017)Accurate needle guidance is essential for a number of magnetic resonance imaging (MRI)-guided percutaneous procedures, such as radiofrequency ablation (RFA) of metastatic liver tumors. A promising technology to obtain ... -
Cardiovascular Catheter With an Expandable Origami Structure
(The American Society of Mechanical Engineers (ASME), 2017)Interventional catheter ablation treatment is a noninvasive approach for normalizing heart rhythm in patients with arrhythmia. Catheter ablation can be assisted with magnetic resonance imaging (MRI) to provide high-contrast ... -
A Human Thermoregulation Simulator for Calibrating Water-Perfused Cooling Pad Systems for Therapeutic Hypothermia
(The American Society of Mechanical Engineers (ASME), 2017)The induction of a mild reduction in body core temperature has been demonstrated to provide neuroprotection for patients who have suffered a medical event resulting in ischemia to the brain or vital organs. Temperatures ... -
Ventricular Assist Devices: Current State and Challenges
(The American Society of Mechanical Engineers (ASME), 2017)Cardiovascular disease (CVD), as the most prevalent human disease, incorporates a broad spectrum of cardiovascular system malfunctions/disorders. While cardiac transplantation is widely acknowledged as the optional treatment ...