Journal of Biomechanical Engineering: Recent submissions
Now showing items 681-700 of 5302
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Constitutive Modeling of Corneal Tissue: Influence of Three-Dimensional Collagen Fiber Microstructure
(The American Society of Mechanical Engineers (ASME), 2020)The cornea, the transparent tissue in the front of the eye, along with the sclera, plays a vital role in protecting the inner structures of the eyeball. The precise shape and mechanical strength of this tissue are mostly ... -
Substrate Stiffness Modulates the Crosstalk Between Mesenchymal Stem Cells and Macrophages
(The American Society of Mechanical Engineers (ASME), 2020)Upon implantation of a biomaterial, mesenchymal stem cells (MSCs) and macrophages contribute to the wound healing response and the regeneration cascade. Although biomaterial properties are known to direct MSC differentiation ... -
Tissue Engineering for Periodontal Ligament Regeneration: Biomechanical Specifications
(The American Society of Mechanical Engineers (ASME), 2020)The periodontal biomechanical environment is very difficult to investigate. By the complex geometry and composition of the periodontal ligament (PDL), its mechanical behavior is very dependent on the type of loading ... -
Laboratory Assessment of a Headband-Mounted Sensor for Measurement of Head Impact Rotational Kinematics
(The American Society of Mechanical Engineers (ASME), 2020)Head impact sensors measure head kinematics in sports, and sensor accuracy is crucial for investigating the potential link between repetitive head loading and clinical outcomes. Many validation studies mount sensors to ... -
Mechanical Consequence of Induced Intervertebral Disc Degeneration in the SPARC-Null Mouse
(The American Society of Mechanical Engineers (ASME), 2020)Intervertebral disc (IVD) degeneration is associated with low back pain (LBP) and accompanied by mechanical changes to the spine. Secreted protein acidic and rich in cysteine (SPARC) is a protein that contributes to the ... -
Effect of Ligament Properties on Nonlinear Dynamics and Wear Prediction of Knee Prostheses
(The American Society of Mechanical Engineers (ASME), 2020)Although wear is known as the primary cause of long-time failure of total knee arthroplasty (TKA), it can be vital in short- and midterm TKA failure due to laxity. One of the reasons leading to joint laxity and instability ... -
A Method to Use Kriging With Large Sets of Control Points to Morph Finite Element Models of the Human Body
(The American Society of Mechanical Engineers (ASME), 2020)As developing finite element (FE) human body models for automotive impact is a time-consuming process, morphing using interpolation methods such as kriging has often been used to rapidly generate models of different shapes ... -
Global Sensitivity Analysis for Patient-Specific Aortic Simulations: The Role of Geometry, Boundary Condition and Large Eddy Simulation Modeling Parameters
(The American Society of Mechanical Engineers (ASME), 2020)Numerical simulations for computational hemodynamics in clinical settings require a combination of many ingredients, mathematical models, solvers and patient-specific data. The sensitivity of the solutions to these factors ... -
Effect of Non-Newtonian Dynamics on the Clearance of Mucus From Bifurcating Lung Airway Models
(The American Society of Mechanical Engineers (ASME), 2020)Mucus hypersecretion is a common pathophysiological manifestation of several obstructive airway diseases in which the mucociliary clearance is impaired, and the airflow generated by a cough or a forced expiratory maneuver ... -
Nine Degree-of-Freedom Kinematic Modeling of the Upper-Limb Complex for Constrained Workspace Evaluation
(The American Society of Mechanical Engineers (ASME), 2020)The design of rehabilitation devices for patients experiencing musculoskeletal disorders (MSDs) requires a great deal of attention. This article aims to develop a comprehensive model of the upper-limb complex to guide the ... -
A Novel, Efficient, Unit Circle-Based, Method for Positioning and Operating Cryo-Surgical Probes in Convex Target Areas
(The American Society of Mechanical Engineers (ASME), 2020)A novel method for positioning and operating needle-like cryo-surgical probes in 2D convex target areas is presented. The method is based on the recorded dynamic performance of a single probe, termed “unit circle,” (UC) ... -
Preliminary Material Evaluation of Flax Fibers for Prosthetic Socket Fabrication
(The American Society of Mechanical Engineers (ASME), 2020)Composite prosthetic sockets are typically made of fiberglass or carbon fiber. These fibers have good mechanical properties, but relatively poor vibration damping. Flax fibers are claimed to have exceptional vibration ... -
Misalignment Error in Cancellous Bone Apparent Elastic Modulus Depends on Bone Volume Fraction and Degree of Anisotropy
(The American Society of Mechanical Engineers (ASME), 2020)Cancellous bone is an anisotropic structure with architectural and mechanical properties that vary due to both skeletal site and disease state. This anisotropy means that, in order to accurately and consistently measure ... -
Pelvic Protection Limiting Lower Limb Flail Reduces Mortality
(The American Society of Mechanical Engineers (ASME), 2020)Pelvic blast injury is one of the most severe patterns of injury to be sustained by casualties of explosions. We have previously identified the mechanism of injury in a shock tube-mediated murine model, linking outward ... -
Study on the Long Bone Failure Behaviors Under the Indenter Rigid-Contact by Experiment Analysis and Subject-Specific Simulation
(The American Society of Mechanical Engineers (ASME), 2020)The bending fracture behaviors of long bone have gained great attention due to the high bending fracture risk during sports events, traffic accidents, and falling incidents, etc. For evaluating bone bending behaviors, most ... -
On the Reliability of Suction Measurements for Skin Characterization
(The American Society of Mechanical Engineers (ASME), 2020)in vivo skin characterization methods were shown to be useful in the detection of microstructural alterations of the dermis due to skin diseases. Specifically, the diagnostic potential of skin suction has been widely ... -
Foot Rotation Gait Modifications Affect Hip and Ankle, But Not Knee, Stance Phase Joint Reaction Forces During Running
(The American Society of Mechanical Engineers (ASME), 2020)Alterations of foot rotation angles have successfully reduced external knee adduction moments during walking and running. However, reductions in knee adduction moments may not result in reductions in knee joint reaction ... -
Hierarchical Validation Prevents Over-Fitting of the Neck Material Model for an Anthropomorphic Test Device Used in Underbody Blast Scenarios
(The American Society of Mechanical Engineers (ASME), 2020)Injury due to underbody loading is increasingly relevant to the safety of the modern warfighter. To accurately evaluate injury risk in this loading modality, a biofidelic anthropomorphic test device (e.g., dummy) is required. ... -
Influence of Material Model and Aortic Root Motion in Finite Element Analysis of Two Exemplary Cases of Proximal Aortic Dissection
(The American Society of Mechanical Engineers (ASME), 2020)The risk of type-A dissection is increased in subjects with connective tissue disorders and dilatation of the proximal aorta. The location and extents of vessel wall tears in these patients could be potentially missed ... -
Magnetohydrodynamic Moving Liquid Plug Within a Microchannel: Analytical Solutions
(The American Society of Mechanical Engineers (ASME), 2020)The wide applications of plug flows in microscale in science and engineering help them attract a great deal recent interest. An analytical study is undertaken here to study the impacts of a transversely applied external ...