Journal of Biomechanical Engineering: Recent submissions
Now showing items 661-680 of 5302
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Direct Osmotic Pressure Measurements in Articular Cartilage Demonstrate Nonideal and Concentration-Dependent Phenomena
(The American Society of Mechanical Engineers (ASME), 2020)The osmotic pressure in articular cartilage serves an important mechanical function in healthy tissue. Its magnitude is thought to play a role in advancing osteoarthritis. The aims of this study were to: (1) isolate and ... -
Direct Measurements of the Wing Kinematics of a Bat in Straight Flight
(The American Society of Mechanical Engineers (ASME), 2020)Bat is the only mammal in the nature that can fly. Compared with birds and insects, bats are quite special in that their wings are formed by an elastic membrane, which renders that the airfoil deforms greatly during ... -
Real-Time Analysis of the Dynamic Foot Function: A Machine Learning and Finite Element Approach
(The American Society of Mechanical Engineers (ASME), 2020)Finite element analysis (FEA) has been widely used to study foot biomechanics and pathological functions or effects of therapeutic solutions. However, development and analysis of such foot modeling is complex and time-consuming. ... -
Individual-Specific Modeling of Rat Optic Nerve Head Biomechanics in Glaucoma
(The American Society of Mechanical Engineers (ASME), 2020)Glaucoma is the second leading cause of blindness worldwide and is characterized by the death of retinal ganglion cells (RGCs), the cells that send vision information to the brain. Their axons exit the eye at the optic ... -
A Parametric Investigation of Corneal Laser Surgery Based on the Multilayer Dynamic Photothermal Model
(The American Society of Mechanical Engineers (ASME), 2020)Corneal laser surgery is a widely used method for the treatment of ocular myopia, hyperopia, and astigmatism. Although it is a well-established technique, the photothermal properties of the cornea are often overlooked, ... -
The Story of Wall Shear Stress in Coronary Artery Atherosclerosis: Biochemical Transport and Mechanotransduction
(The American Society of Mechanical Engineers (ASME), 2020)Coronary artery atherosclerosis is a local, multifactorial, complex disease, and the leading cause of death in the US. Complex interactions between biochemical transport and biomechanical forces influence disease growth. ... -
Identification of Postural Controllers in Human Standing Balance
(The American Society of Mechanical Engineers (ASME), 2020)Standing balance is a simple motion task for healthy humans but the actions of the central nervous system (CNS) have not been described by generalized and sufficiently sophisticated control laws. While system identification ... -
Quantifying Throw Counts and Intensities Throughout a Season in Youth Baseball Players: A Pilot Study
(The American Society of Mechanical Engineers (ASME), 2020)Overuse injuries in youth baseball players due to throwing are at an all-time high. Traditional methods of tracking player throwing load only count in-game pitches and therefore leave many throws unaccounted for. Miniature ... -
GBT440 Increases Hematocrit and Improves Biventricular Function in Berkeley Sickle Cell Disease Mice
(The American Society of Mechanical Engineers (ASME), 2020)Sickle cell disease (SCD) is a hereditary blood disorder affecting millions of people in which red blood cells (RBCs) become sickled and lyse easily driven by polymerization of hemoglobin. Chronically, SCD causes anemia ... -
A Hemodynamic Comparison of Myocardial Bridging and Coronary Atherosclerotic Stenosis: A Computational Model With Experimental Evaluation
(The American Society of Mechanical Engineers (ASME), 2021)Myocardial bridging (MB) and coronary atherosclerotic stenosis can impair coronary blood flow and may cause myocardial ischemia or even heart attack. It remains unclear how MB and stenosis are similar or different regarding ... -
Hip Joint Contact Loading and Muscle Forces During Running With a Transtibial Amputation
(The American Society of Mechanical Engineers (ASME), 2021)People with unilateral transtibial amputations (TTA) have greater risks of bilateral hip osteoarthritis, related to asymmetric biomechanics compared to people without TTA. Running is beneficial for physical health and is ... -
Calibration of an Electrical Analog Model of Liver Hemodynamics in Fontan Patients
(The American Society of Mechanical Engineers (ASME), 2020)Fontan associated liver disease is a common complication in patients with Fontan circulation, who were born with a single functioning heart ventricle. The hepatic venous pressure gradient (HVPG) is used to assess liver ... -
A Study to Compare the Efficacy of a Biodegradable Dynamic Fixation System With Titanium Devices in Posterior Spinal Fusion Between Articular Processes in a Canine Model
(The American Society of Mechanical Engineers (ASME), 2020)The objective of this study was to apply a biodegradable dynamic fixation system (BDFS) for lumbar fusion between articular processes and compare the fusion results and biomechanical changes with those of conventional rigid ... -
Stent-Induced Vascular Remodeling in Two-Step Stent-Assisted Coiling Treatment of Brain Aneurysms: A Closer Look Into the Hemodynamic Changes During the Stent Healing Period
(The American Society of Mechanical Engineers (ASME), 2020)Stenting has become an important adjunctive tool for assisting coil embolization in complex-shaped intracranial aneurysms. However, as a secondary effect, stent deployment has been related to both immediate and delayed ... -
Determining Isolated Thumb Forces in Osteoarthritic and Healthy Persons
(The American Society of Mechanical Engineers (ASME), 2020)Carpometacarpal (CMC) osteoarthritis (OA) can dramatically impair thumb function resulting in the inability to complete basic tasks. Development of a method to detect thumb forces changes is essential to understand of the ... -
Assessment of Thorax Finite Element Model Response for Behind Armor Blunt Trauma Impact Loading Using an Epidemiological Database
(The American Society of Mechanical Engineers (ASME), 2020)Nonperforating ballistic impacts on thoracic armor can cause blunt injuries, known as behind-armor blunt trauma (BABT). To evaluate the potential for this injury, the back face deformation (BFD) imprinted into a clay backing ... -
Predictions of Anterior Cruciate Ligament Dynamics From Subject-Specific Musculoskeletal Models and Dynamic Biplane Radiography
(The American Society of Mechanical Engineers (ASME), 2020)In vivo knee ligament forces are important to consider for informing rehabilitation or clinical interventions. However, they are difficult to directly measure during functional activities. Musculoskeletal models and ... -
Modeling Pulse Wave Propagation Through a Stenotic Artery With Fluid Structure Interaction: A Validation Study Using Ultrasound Pulse Wave Imaging
(The American Society of Mechanical Engineers (ASME), 2020)Pulse wave imaging (PWI) is an ultrasound-based method that allows spatiotemporal mapping of the arterial pulse wave propagation, from which the local pulse wave velocity (PWV) can be derived. Recent reports indicate that ... -
Computational Investigation of Protein Photoinactivation by Molecular Hyperthermia
(The American Society of Mechanical Engineers (ASME), 2020)To precisely control protein activity in a living system is a challenging yet long-pursued objective in biomedical sciences. Recently, we have developed a new approach named molecular hyperthermia (MH) to photoinactivate ... -
Experimental Demonstration of the Lower Leg Trajectory Error Framework Using Physiological Data as Inputs
(The American Society of Mechanical Engineers (ASME), 2020)While many studies have attempted to characterize the mechanical behavior of passive prosthetic feet to understand their influence on amputee gait, the relationship between mechanical design and biomechanical performance ...