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    Abnormalities in the Membrane Material Properties of Hereditary Spherocytes

    Source: Journal of Biomechanical Engineering:;1980:;volume( 102 ):;issue: 003::page 240
    Author:
    R. E. Waugh
    ,
    P. L. La Celle
    DOI: 10.1115/1.3149580
    Publisher: The American Society of Mechanical Engineers (ASME)
    Abstract: Mechanical measurements of intrinsic membrane material properties are used to characterize the defect in hereditary spherocyte membrane at a continuum level. The value of the surface elastic shear modulus is two-thirds as large as normal values, and the value of the yield shear resultant is one-third as large as normal values. The viscosity of the surface above the elastic-plastic transition appears normal. Under similar geometric conditions, the force required to fragment a hereditary spherocyte is about one-third as large as the force required to fragment a normal cell.
    keyword(s): Materials properties , Membranes , Force , Measurement , Viscosity , Shear (Mechanics) AND Shear modulus ,
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      Abnormalities in the Membrane Material Properties of Hereditary Spherocytes

    URI
    http://yetl.yabesh.ir/yetl1/handle/yetl/93024
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    • Journal of Biomechanical Engineering

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    contributor authorR. E. Waugh
    contributor authorP. L. La Celle
    date accessioned2017-05-08T23:08:13Z
    date available2017-05-08T23:08:13Z
    date copyrightAugust, 1980
    date issued1980
    identifier issn0148-0731
    identifier otherJBENDY-25658#240_1.pdf
    identifier urihttp://yetl.yabesh.ir/yetl/handle/yetl/93024
    description abstractMechanical measurements of intrinsic membrane material properties are used to characterize the defect in hereditary spherocyte membrane at a continuum level. The value of the surface elastic shear modulus is two-thirds as large as normal values, and the value of the yield shear resultant is one-third as large as normal values. The viscosity of the surface above the elastic-plastic transition appears normal. Under similar geometric conditions, the force required to fragment a hereditary spherocyte is about one-third as large as the force required to fragment a normal cell.
    publisherThe American Society of Mechanical Engineers (ASME)
    titleAbnormalities in the Membrane Material Properties of Hereditary Spherocytes
    typeJournal Paper
    journal volume102
    journal issue3
    journal titleJournal of Biomechanical Engineering
    identifier doi10.1115/1.3149580
    journal fristpage240
    journal lastpage246
    identifier eissn1528-8951
    keywordsMaterials properties
    keywordsMembranes
    keywordsForce
    keywordsMeasurement
    keywordsViscosity
    keywordsShear (Mechanics) AND Shear modulus
    treeJournal of Biomechanical Engineering:;1980:;volume( 102 ):;issue: 003
    contenttypeFulltext
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