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contributor authorDavidson, Haleigh
contributor authorScardino, Brooke
contributor authorGamage, Peshala Thibbotuwawa
contributor authorTaebi, Amirtahà
date accessioned2024-04-24T22:35:57Z
date available2024-04-24T22:35:57Z
date copyright9/26/2023 12:00:00 AM
date issued2023
identifier issn2572-7958
identifier otherjesmdt_007_01_011008.pdf
identifier urihttp://yetl.yabesh.ir/yetl1/handle/yetl/4295512
description abstractCerebral aneurysms are potentially life-threatening cerebrovascular conditions where a weakened blood vessel in the brain bulges or protrudes over time. The most common way to treat aneurysms is surgical clipping, an approach where blood flow to the aneurysm is blocked by a permanently placed clip on the artery. However, not all aneurysms are identical; thus, there has been a need for patient-specific treatment options, where each aneurysm is treated based on its individual characteristics. Computational fluid dynamics (CFD) modeling can offer insights to predict how different treatment procedures will affect cerebral hemodynamics. In that regard, the goal of this pilot study was to investigate the flow characteristics and hemodynamic parameters in cerebral arteries before and after neurosurgical clipping. For this purpose, two patient-specific cerebral artery geometries with at least one aneurysm at the middle cerebral artery bifurcation were selected from an online dataset. A companion postclipping model was created for each geometry by removing the aneurysm from the original geometry. Tetrahedral mesh elements were then generated and CFD simulations were conducted to compare the blood velocity profile, secondary flow, flow streamline, and wall shear stress in the computational models with and without aneurysm. Results showed that the clipping treatment led to changes in the velocity profiles, secondary flow structures, and wall shear stress in the middle cerebral artery. In conclusion, our results suggest that CFD modeling can assist in predicting hemodynamic parameters prior to treatment, thus facilitating more tailored planning for each patient’s treatment.
publisherThe American Society of Mechanical Engineers (ASME)
titleVariations of Middle Cerebral Artery Hemodynamics Due to Aneurysm Clipping Surgery
typeJournal Paper
journal volume7
journal issue1
journal titleJournal of Engineering and Science in Medical Diagnostics and Therapy
identifier doi10.1115/1.4063204
journal fristpage11008-1
journal lastpage11008-6
page6
treeJournal of Engineering and Science in Medical Diagnostics and Therapy:;2023:;volume( 007 ):;issue: 001
contenttypeFulltext


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