The Influence of Axial Compression on the Cellular and Mechanical Function of Spinal Tissues; Emphasis on the Nucleus Pulposus and Annulus Fibrosus: A ReviewSource: Journal of Biomechanical Engineering:;2021:;volume( 143 ):;issue: 005::page 050802-1DOI: 10.1115/1.4049749Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: In light of the correlation between chronic back pain and intervertebral disc (IVD) degeneration, this literature review seeks to illustrate the importance of the hydraulic response across the nucleus pulposus (NP)-annulus fibrosus (AF) interface, by synthesizing current information regarding injurious biomechanics of the spine, stemming from axial compression. Damage to vertebrae, endplates (EPs), the NP, and the AF, can all arise from axial compression, depending on the segment's posture, the manner in which it is loaded, and the physiological state of tissue. Therefore, this movement pattern was selected to illustrate the importance of the bracing effect of a pressurized NP on the AF, and how injuries interrupting support to the AF may contribute to IVD degeneration.
|
Collections
Show full item record
| contributor author | McMorran, John G. | |
| contributor author | Gregory, Diane E. | |
| date accessioned | 2022-02-05T22:36:51Z | |
| date available | 2022-02-05T22:36:51Z | |
| date copyright | 3/4/2021 12:00:00 AM | |
| date issued | 2021 | |
| identifier issn | 0148-0731 | |
| identifier other | bio_143_05_050802.pdf | |
| identifier uri | http://yetl.yabesh.ir/yetl1/handle/yetl/4277847 | |
| description abstract | In light of the correlation between chronic back pain and intervertebral disc (IVD) degeneration, this literature review seeks to illustrate the importance of the hydraulic response across the nucleus pulposus (NP)-annulus fibrosus (AF) interface, by synthesizing current information regarding injurious biomechanics of the spine, stemming from axial compression. Damage to vertebrae, endplates (EPs), the NP, and the AF, can all arise from axial compression, depending on the segment's posture, the manner in which it is loaded, and the physiological state of tissue. Therefore, this movement pattern was selected to illustrate the importance of the bracing effect of a pressurized NP on the AF, and how injuries interrupting support to the AF may contribute to IVD degeneration. | |
| publisher | The American Society of Mechanical Engineers (ASME) | |
| title | The Influence of Axial Compression on the Cellular and Mechanical Function of Spinal Tissues; Emphasis on the Nucleus Pulposus and Annulus Fibrosus: A Review | |
| type | Journal Paper | |
| journal volume | 143 | |
| journal issue | 5 | |
| journal title | Journal of Biomechanical Engineering | |
| identifier doi | 10.1115/1.4049749 | |
| journal fristpage | 050802-1 | |
| journal lastpage | 050802-11 | |
| page | 11 | |
| tree | Journal of Biomechanical Engineering:;2021:;volume( 143 ):;issue: 005 | |
| contenttype | Fulltext |