| contributor author | Park, Seungman | |
| contributor author | Jung, Wei-Hung | |
| contributor author | Pittman, Matthew | |
| contributor author | Chen, Junjie | |
| contributor author | Chen, Yun | |
| date accessioned | 2022-02-04T21:56:45Z | |
| date available | 2022-02-04T21:56:45Z | |
| date copyright | 8/31/2020 12:00:00 AM | |
| date issued | 2020 | |
| identifier issn | 0148-0731 | |
| identifier other | ep_142_04_041001.pdf | |
| identifier uri | http://yetl.yabesh.ir/yetl1/handle/yetl/4274577 | |
| description abstract | Cells sense biophysical cues in the micro-environment and respond to the cues biochemically and biophysically. Proper responses from cells are critical to maintain the homeostasis in the body. Abnormal biophysical cues will cause pathological development in the cells; pathological or aging cells, on the other hand, can alter their micro-environment to become abnormal. In this minireview, we discuss four important biophysical cues of the micro-environment—stiffness, curvature, extracellular matrix (ECM) architecture and viscosity—in terms of their roles in health, aging, and diseases. | |
| publisher | The American Society of Mechanical Engineers (ASME) | |
| title | The Effects of Stiffness, Fluid Viscosity, and Geometry of Microenvironment in Homeostasis, Aging, and Diseases: A Brief Review | |
| type | Journal Paper | |
| journal volume | 142 | |
| journal issue | 10 | |
| journal title | Journal of Biomechanical Engineering | |
| identifier doi | 10.1115/1.4048110 | |
| journal fristpage | 0100804-1 | |
| journal lastpage | 0100804-11 | |
| page | 11 | |
| tree | Journal of Biomechanical Engineering:;2020:;volume( 142 ):;issue: 010 | |
| contenttype | Fulltext | |