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    Optimized Time-Resolved Echo Particle Image Velocimetry– Particle Tracking Velocimetry Measurements Elucidate Blood Flow in Patients With Left Ventricular Thrombus

    Source: Journal of Biomechanical Engineering:;2018:;volume( 140 ):;issue: 004::page 41010
    Author:
    Sampath, Kaushik
    ,
    Harfi, Thura T.
    ,
    George, Richard T.
    ,
    Katz, Joseph
    DOI: 10.1115/1.4038886
    Publisher: The American Society of Mechanical Engineers (ASME)
    Abstract: Contrast ultrasound is a widely used clinical tool to obtain real-time qualitative blood flow assessments in the heart, liver, etc. Echocardiographic particle image velocimetry (echo-PIV) is a technique for obtaining quantitative velocity maps from contrast ultrasound images. However, unlike optical particle image velocimetry (PIV), routine echo images are prone to nonuniform spatiotemporal variations in tracer distribution, making analysis difficult for standard PIV algorithms. This study introduces optimized procedures that integrate image enhancement, PIV, and particle tracking velocimetry (PTV) to obtain reliable time-resolved two-dimensional (2D) velocity distributions. During initial PIV analysis, multiple results are obtained by varying processing parameters. Optimization involving outlier removal and smoothing is used to select the correct vector. These results are used in a multiparameter PTV procedure. To demonstrate their clinical value, the procedures are implemented to obtain velocity and vorticity distributions over multiple cardiac cycles using images acquired from four left ventricular thrombus (LVT) patients. Phase-averaged data elucidate flow structure evolution over the cycle and are used to calculate penetration depth and strength of left ventricular (LV) vortices, as well as apical velocity induced by them. The present data are consistent with previous time-averaged results for the minimum vortex penetration depth associated with LVT occurrence. However, due to decay and fragmentation of LV vortices, as they migrate away from the mitral annulus, in two cases with high penetration, there is still poor washing near the resolved clot throughout the cycle. Hence, direct examination of entire flow evolution may be useful for assessing risk of LVT relapse before prescribing anticoagulants.
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      Optimized Time-Resolved Echo Particle Image Velocimetry– Particle Tracking Velocimetry Measurements Elucidate Blood Flow in Patients With Left Ventricular Thrombus

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    contributor authorSampath, Kaushik
    contributor authorHarfi, Thura T.
    contributor authorGeorge, Richard T.
    contributor authorKatz, Joseph
    date accessioned2019-02-28T11:11:18Z
    date available2019-02-28T11:11:18Z
    date copyright2/12/2018 12:00:00 AM
    date issued2018
    identifier issn0148-0731
    identifier otherbio_140_04_041010.pdf
    identifier urihttp://yetl.yabesh.ir/yetl1/handle/yetl/4253613
    description abstractContrast ultrasound is a widely used clinical tool to obtain real-time qualitative blood flow assessments in the heart, liver, etc. Echocardiographic particle image velocimetry (echo-PIV) is a technique for obtaining quantitative velocity maps from contrast ultrasound images. However, unlike optical particle image velocimetry (PIV), routine echo images are prone to nonuniform spatiotemporal variations in tracer distribution, making analysis difficult for standard PIV algorithms. This study introduces optimized procedures that integrate image enhancement, PIV, and particle tracking velocimetry (PTV) to obtain reliable time-resolved two-dimensional (2D) velocity distributions. During initial PIV analysis, multiple results are obtained by varying processing parameters. Optimization involving outlier removal and smoothing is used to select the correct vector. These results are used in a multiparameter PTV procedure. To demonstrate their clinical value, the procedures are implemented to obtain velocity and vorticity distributions over multiple cardiac cycles using images acquired from four left ventricular thrombus (LVT) patients. Phase-averaged data elucidate flow structure evolution over the cycle and are used to calculate penetration depth and strength of left ventricular (LV) vortices, as well as apical velocity induced by them. The present data are consistent with previous time-averaged results for the minimum vortex penetration depth associated with LVT occurrence. However, due to decay and fragmentation of LV vortices, as they migrate away from the mitral annulus, in two cases with high penetration, there is still poor washing near the resolved clot throughout the cycle. Hence, direct examination of entire flow evolution may be useful for assessing risk of LVT relapse before prescribing anticoagulants.
    publisherThe American Society of Mechanical Engineers (ASME)
    titleOptimized Time-Resolved Echo Particle Image Velocimetry– Particle Tracking Velocimetry Measurements Elucidate Blood Flow in Patients With Left Ventricular Thrombus
    typeJournal Paper
    journal volume140
    journal issue4
    journal titleJournal of Biomechanical Engineering
    identifier doi10.1115/1.4038886
    journal fristpage41010
    journal lastpage041010-14
    treeJournal of Biomechanical Engineering:;2018:;volume( 140 ):;issue: 004
    contenttypeFulltext
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    DSpace software copyright © 2002-2015  DuraSpace
    نرم افزار کتابخانه دیجیتال "دی اسپیس" فارسی شده توسط یابش برای کتابخانه های ایرانی | تماس با یابش
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