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    Deformation Compensation During Buoyancy-Enabled Inkjet Printing of Three-Dimensional Soft Tubular Structures

    Source: Journal of Manufacturing Science and Engineering:;2018:;volume( 140 ):;issue: 001::page 11011
    Author:
    Christensen, Kyle
    ,
    Zhang, Zhengyi
    ,
    Xu, Changxue
    ,
    Huang, Yong
    DOI: 10.1115/1.4037996
    Publisher: The American Society of Mechanical Engineers (ASME)
    Abstract: Of various tissues being fabricated using bioprinting, three-dimensional (3D) soft tubular structures have often been the focus since they address the need for printable vasculature throughout a thick tissue and offer potential as perfusable platforms for biological studies. Drop-on-demand inkjetting has been favored as an effective technique to print such 3D soft tubular structures from various hydrogel bioinks. During the buoyancy-enabled inkjet fabrication of hydrogel-based soft tubular structures, they remain submerged in a solution, which crosslinks the printed structures and provides a supporting buoyant force. However, because of the low stiffness of the structures, the structural deformation of printed tubes poses a significant challenge to the process effectiveness and efficiency. To overcome this structural deformation during buoyancy-enabled inkjet printing, predictive compensation approaches are developed to incorporate deformation allowance into the designed shape. Circumferential deformation is addressed by a four-zone approach, which includes base, circular, vertical, and spanning zones for the determination of a designed cross section or compensated printing path. Axial deformation is addressed by the modification of the proposed circumferential compensation based on the distance of a given cross section to the junction of a branching tube. These approaches are found to enable the successful fabrication of straight and branching alginate tubular structures with nearly ideal geometry, providing a good foundation for the wide implementation of the buoyancy-enabled inkjetting technique. While inkjetting is studied herein as a model bioprinting process, the resulting knowledge also applies to other buoyancy-enabled bioprinting techniques.
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      Deformation Compensation During Buoyancy-Enabled Inkjet Printing of Three-Dimensional Soft Tubular Structures

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    contributor authorChristensen, Kyle
    contributor authorZhang, Zhengyi
    contributor authorXu, Changxue
    contributor authorHuang, Yong
    date accessioned2019-02-28T11:02:02Z
    date available2019-02-28T11:02:02Z
    date copyright11/17/2017 12:00:00 AM
    date issued2018
    identifier issn1087-1357
    identifier othermanu_140_01_011011.pdf
    identifier urihttp://yetl.yabesh.ir/yetl1/handle/yetl/4251934
    description abstractOf various tissues being fabricated using bioprinting, three-dimensional (3D) soft tubular structures have often been the focus since they address the need for printable vasculature throughout a thick tissue and offer potential as perfusable platforms for biological studies. Drop-on-demand inkjetting has been favored as an effective technique to print such 3D soft tubular structures from various hydrogel bioinks. During the buoyancy-enabled inkjet fabrication of hydrogel-based soft tubular structures, they remain submerged in a solution, which crosslinks the printed structures and provides a supporting buoyant force. However, because of the low stiffness of the structures, the structural deformation of printed tubes poses a significant challenge to the process effectiveness and efficiency. To overcome this structural deformation during buoyancy-enabled inkjet printing, predictive compensation approaches are developed to incorporate deformation allowance into the designed shape. Circumferential deformation is addressed by a four-zone approach, which includes base, circular, vertical, and spanning zones for the determination of a designed cross section or compensated printing path. Axial deformation is addressed by the modification of the proposed circumferential compensation based on the distance of a given cross section to the junction of a branching tube. These approaches are found to enable the successful fabrication of straight and branching alginate tubular structures with nearly ideal geometry, providing a good foundation for the wide implementation of the buoyancy-enabled inkjetting technique. While inkjetting is studied herein as a model bioprinting process, the resulting knowledge also applies to other buoyancy-enabled bioprinting techniques.
    publisherThe American Society of Mechanical Engineers (ASME)
    titleDeformation Compensation During Buoyancy-Enabled Inkjet Printing of Three-Dimensional Soft Tubular Structures
    typeJournal Paper
    journal volume140
    journal issue1
    journal titleJournal of Manufacturing Science and Engineering
    identifier doi10.1115/1.4037996
    journal fristpage11011
    journal lastpage011011-10
    treeJournal of Manufacturing Science and Engineering:;2018:;volume( 140 ):;issue: 001
    contenttypeFulltext
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    DSpace software copyright © 2002-2015  DuraSpace
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