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    Extending the Power-Law Hemolysis Model to Complex Flows

    Source: Journal of Biomechanical Engineering:;2016:;volume( 138 ):;issue: 012::page 124504
    Author:
    Faghih, Mohammad M.
    ,
    Keith Sharp, M.
    DOI: 10.1115/1.4034786
    Publisher: The American Society of Mechanical Engineers (ASME)
    Abstract: Hemolysis (damage to red blood cells) is a long-standing problem in blood contacting devices, and its prediction has been the goal of considerable research. The most popular model relating hemolysis to fluid stresses is the power-law model, which was developed from experiments in pure shear only. In the absence of better data, this model has been extended to more complex flows by replacing the shear stress in the power-law equation with a von Mises-like scalar stress. While the validity of the scalar stress also remains to be confirmed, inconsistencies exist in its application, in particular, two forms that vary by a factor of 2 have been used. This article will clarify the proper extension of the power law to complex flows in a way that maintains correct results in the limit of pure shear.
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      Extending the Power-Law Hemolysis Model to Complex Flows

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    contributor authorFaghih, Mohammad M.
    contributor authorKeith Sharp, M.
    date accessioned2017-11-25T07:18:09Z
    date available2017-11-25T07:18:09Z
    date copyright2016/11/04
    date issued2016
    identifier issn0148-0731
    identifier otherbio_138_12_124504.pdf
    identifier urihttp://138.201.223.254:8080/yetl1/handle/yetl/4234997
    description abstractHemolysis (damage to red blood cells) is a long-standing problem in blood contacting devices, and its prediction has been the goal of considerable research. The most popular model relating hemolysis to fluid stresses is the power-law model, which was developed from experiments in pure shear only. In the absence of better data, this model has been extended to more complex flows by replacing the shear stress in the power-law equation with a von Mises-like scalar stress. While the validity of the scalar stress also remains to be confirmed, inconsistencies exist in its application, in particular, two forms that vary by a factor of 2 have been used. This article will clarify the proper extension of the power law to complex flows in a way that maintains correct results in the limit of pure shear.
    publisherThe American Society of Mechanical Engineers (ASME)
    titleExtending the Power-Law Hemolysis Model to Complex Flows
    typeJournal Paper
    journal volume138
    journal issue12
    journal titleJournal of Biomechanical Engineering
    identifier doi10.1115/1.4034786
    journal fristpage124504
    journal lastpage124504-4
    treeJournal of Biomechanical Engineering:;2016:;volume( 138 ):;issue: 012
    contenttypeFulltext
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