Journal of Biomechanical Engineering: Recent submissions
Now showing items 101-120 of 5207
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The Lymphatic Vascular System: Does Nonuniform Lymphangion Length Limit Flow-Rate?
(The American Society of Mechanical Engineers (ASME), 2024)A previously developed model of a lymphatic vessel as a chain of lymphangions was investigated to determine whether lymphangions of unequal length reduce pumping relative to a similar chain of equal-length ones. The model ... -
Unsupervised Denoising and Super-Resolution of Vascular Flow Data by Physics-Informed Machine Learning
(The American Society of Mechanical Engineers (ASME), 2024)We present an unsupervised deep learning method to perform flow denoising and super-resolution without high-resolution labels. We demonstrate the ability of a single model to reconstruct three-dimensional stenosis and ... -
Predicting Tibia-Fibula Geometry and Density From Anatomical Landmarks Via Statistical Appearance Model: Influence of Errors on Finite Element-Calculated Bone Strain
(The American Society of Mechanical Engineers (ASME), 2024)State-of-the-art participant-specific finite element models require advanced medical imaging to quantify bone geometry and density distribution; access to and cost of imaging is prohibitive to the use of this approach. ... -
Influence of Breath-Mimicking Ventilated Incubation on Three-Dimensional Bioprinted Respiratory Tissue Scaffolds
(The American Society of Mechanical Engineers (ASME), 2024)Development of respiratory tissue constructs is challenging due to the complex structure of native respiratory tissue and the unique biomechanical conditions induced by breathing. While studies have shown that the inclusion ... -
Surface Reaction of Electroosmotic Flow-Driven Free Antigens With Immobilized Magnetic-Microbeads-Tagged-Antibodies in Microchannels
(The American Society of Mechanical Engineers (ASME), 2024)Immunoassays based on reactions between target pathogen (antigen; Ag) and antibody (Ab) are frequently used for Ag detection. An external magnetic field was used to immobilize magnetic microbeads-tagged-antibodies (mMB-Ab) ... -
Estimation of Injury Limits at Vulnerable Impact Locations Along the Forearm Via THUMS AM50 Finite Element Model at Airbag Loading Rates
(The American Society of Mechanical Engineers (ASME), 2024)Side and frontal airbag deployment represents the main injury mechanism to the upper extremity during automotive collisions. Previous dynamic injury limit research has been limited to testing the forearm at either the ... -
Consequence of Red Blood Cells Deformability on Heat Sink Effect of Blood in a Three-Dimensional Bifurcated Vessel
(The American Society of Mechanical Engineers (ASME), 2024)Several diseases like Sickle Cell Anemia, Thalassemia, Hereditary Spherocytosis, Malaria, and Micro-angiopathic Hemolytic Anemia can alter the normal shape of red blood cells (RBCs). The objective of this study is to gain ... -
Announcing the 2022 Richard Skalak Award Editors' Choice Papers
(The American Society of Mechanical Engineers (ASME), 2024)Each year,1 the associate editors of the ASME Journal of Biomechanical Engineering identify the most meritorious papers published in the Journal in the previous calendar year. An external committee then selects the best ... -
Feasibility Study of Experimental Protocol for the Time-Dependent Mechanical Response of Synthetic Tibia
(The American Society of Mechanical Engineers (ASME), 2024)In this research, an experimental biomechanics construct was developed to reveal the mechanics of distal tibial fracture by submitting synthetic tibiae to cyclic loading, resulting in a combined stress state due to axial ... -
Remodeling of Murine Branch Pulmonary Arteries Under Chronic Hypoxia and Short-Term Normoxic Recovery
(The American Society of Mechanical Engineers (ASME), 2024)Chronic hypoxia plays a central role in diverse pulmonary pathologies, but its effects on longitudinal changes in the biomechanical behavior of proximal pulmonary arteries remain poorly understood. Similarly, effects of ... -
A Histomorphometric and Computational Investigation of the Stabilizing Role of Pectinate Ligaments in the Aqueous Outflow Pathway
(The American Society of Mechanical Engineers (ASME), 2024)Murine models are commonly used to study glaucoma, the leading cause of irreversible blindness. Glaucoma is associated with elevated intra-ocular pressure (IOP), which is regulated by the tissues of the aqueous outflow ... -
Accurate Temperature Reconstruction in Radiofrequency Ablation for Atherosclerotic Plaques Based on Inverse Heat Transfer Analysis
(The American Society of Mechanical Engineers (ASME), 2024)Radio frequency ablation has emerged as a widely accepted treatment for atherosclerotic plaques. However, monitoring the temperature field distribution in the blood vessel wall during this procedure presents challenges. ... -
Influence of Walking Over Unexpected Uneven Terrain on Joint Loading for Individuals With Transtibial Amputation
(The American Society of Mechanical Engineers (ASME), 2024)Individuals with transtibial amputation (TTA) experience asymmetric lower-limb loading which can lead to joint pain and injuries. However, it is unclear how walking over unexpected uneven terrain affects their loading ... -
General Muscle Torque Generator Model for a Two Degree-of-Freedom Shoulder Joint
(The American Society of Mechanical Engineers (ASME), 2024)Muscle torque generators (MTGs) have been developed as an alternative to muscle-force models, reducing the muscle-force model complexity to a single torque at the joint. Current MTGs can only be applied to single ... -
In Silico Investigation of Biomechanical Response of a Human Brain Subjected to Primary Blast
(The American Society of Mechanical Engineers (ASME), 2024)The brain response to the explosion-induced primary blast waves is actively sought. Over the past decade, reasonable progress has been made in the fundamental understanding of blast traumatic brain injury (bTBI) using head ... -
Quantification of Cartilage Poroelastic Material Properties Via Analysis of Loading-Induced Cell Death
(The American Society of Mechanical Engineers (ASME), 2024)Articular cartilage (AC) is a load-bearing tissue that covers long bones in synovial joints. The biphasic/poroelastic mechanical properties of AC help it to protect joints by distributing loads, absorbing impact forces, ... -
Assessment of Left Lung Remodeling With Magnetic Resonance Imaging in a Murine Model Following Exposure to Douglas Fir Smoke
(The American Society of Mechanical Engineers (ASME), 2024)Wildland firefighters (WLFFs) experience lung function decline due to occupational exposure to fire smoke. WLFFs typically do not wear respiratory personal protective equipment, and if they do, it is a simple bandana, which ... -
Aged Tendons Exhibit Altered Mechanisms of Strain-Dependent Extracellular Matrix Remodeling
(The American Society of Mechanical Engineers (ASME), 2024)Aging is a primary risk factor for degenerative tendon injuries, yet the etiology and progression of this degeneration are poorly understood. While aged tendons have innate cellular differences that support a reduced ability ... -
Parametric Solid Models of the At-Term Uterus From Magnetic Resonance Images
(The American Society of Mechanical Engineers (ASME), 2024)Birthing mechanics are poorly understood, though many injuries during childbirth are mechanical, like fetal and maternal tissue damage. Several biomechanical simulation models of parturition have been proposed to investigate ... -
Validation of Dynamic 3D MRI for Urodynamics Assessment Using an Anatomically Realistic In Vitro Model of the Bladder
(The American Society of Mechanical Engineers (ASME), 2024)Lowery urinary tract symptoms (LUTS) affect a large majority of the aging population. 3D Dynamic MRI shows promise as a noninvasive diagnostic tool that can assess bladder anatomy and function (urodynamics) while overcoming ...