| description abstract | We observe that posing the inverse problem as a constrained minimization problem under regularization leads to boundary dependent solutions. In this paper, we propose a modified objective function and show with 2D examples that our method works well to reduce boundary sensitive solutions. The examples consist of two stiff inclusions embedded in a softer unit square. These inclusions could be representative of tumors, which are in general stiffer than their background tissues, thus could potentially be detected based on their stiffness contrast. We modify the objective function for the displacement correlation term by weighting it with a function that depends on the strain field. In a simplified 1D coupled model, we derive an analytical expression and observe the same trends in the reconstructions as for the 2D model. The analysis in this paper is confined to inclusions of similar size and may not overlap when projected on the horizontal axis. They may, however, vary in position along the vertical axis. Furthermore, our analysis holds for an arbitrary number of inclusions having distinct stiffness values. Finally, to increase the overall contrast of the tumors and simultaneously improve the smoothness, we solve the regularized inverse problem in a posterior step, utilizing a spatially varying regularization factor. | |
