contributor author | Dreher, Rachel | |
contributor author | Starly, Binil | |
date accessioned | 2017-05-09T01:22:12Z | |
date available | 2017-05-09T01:22:12Z | |
date issued | 2015 | |
identifier issn | 1949-2944 | |
identifier other | nano_006_02_021004.pdf | |
identifier uri | http://yetl.yabesh.ir/yetl/handle/yetl/159264 | |
description abstract | In this study, we report the bioprinting of a threedimensional (3D) heterogeneous conduit structure encapsulating PC12 neural cells. A core–shellbased hybrid construct is fabricated by combining electrospinning, polymer extrusion, and cellbased bioprinting processes to create a multiscale and multimaterial conduit structure. PC12 nerve cells were shown to be printed with high cell viability (>95%) and to proliferate within the rolled construct at a rate consistent with traditional twodimensional (2D) culture. Light microscopy and scanning electron microscopy (SEM) have also shown encapsulation of cells within the printed alginate gel and an even cell distribution throughout the heterogeneous cellular construct. | |
publisher | The American Society of Mechanical Engineers (ASME) | |
title | Biofabrication of Multimaterial Three Dimensional Constructs Embedded With Patterned Alginate Strands Encapsulating PC12 Neural Cell Lines | |
type | Journal Paper | |
journal volume | 6 | |
journal issue | 2 | |
journal title | Journal of Nanotechnology in Engineering and Medicine | |
identifier doi | 10.1115/1.4031173 | |
journal fristpage | 21004 | |
journal lastpage | 21004 | |
identifier eissn | 1949-2952 | |
tree | Journal of Nanotechnology in Engineering and Medicine:;2015:;volume( 006 ):;issue: 002 | |
contenttype | Fulltext | |