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    Biofabrication of Multimaterial Three Dimensional Constructs Embedded With Patterned Alginate Strands Encapsulating PC12 Neural Cell Lines

    Source: Journal of Nanotechnology in Engineering and Medicine:;2015:;volume( 006 ):;issue: 002::page 21004
    Author:
    Dreher, Rachel
    ,
    Starly, Binil
    DOI: 10.1115/1.4031173
    Publisher: The American Society of Mechanical Engineers (ASME)
    Abstract: In this study, we report the bioprinting of a threedimensional (3D) heterogeneous conduit structure encapsulating PC12 neural cells. A core–shellbased hybrid construct is fabricated by combining electrospinning, polymer extrusion, and cellbased bioprinting processes to create a multiscale and multimaterial conduit structure. PC12 nerve cells were shown to be printed with high cell viability (>95%) and to proliferate within the rolled construct at a rate consistent with traditional twodimensional (2D) culture. Light microscopy and scanning electron microscopy (SEM) have also shown encapsulation of cells within the printed alginate gel and an even cell distribution throughout the heterogeneous cellular construct.
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      Biofabrication of Multimaterial Three Dimensional Constructs Embedded With Patterned Alginate Strands Encapsulating PC12 Neural Cell Lines

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    http://yetl.yabesh.ir/yetl1/handle/yetl/159264
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    contributor authorDreher, Rachel
    contributor authorStarly, Binil
    date accessioned2017-05-09T01:22:12Z
    date available2017-05-09T01:22:12Z
    date issued2015
    identifier issn1949-2944
    identifier othernano_006_02_021004.pdf
    identifier urihttp://yetl.yabesh.ir/yetl/handle/yetl/159264
    description abstractIn this study, we report the bioprinting of a threedimensional (3D) heterogeneous conduit structure encapsulating PC12 neural cells. A core–shellbased hybrid construct is fabricated by combining electrospinning, polymer extrusion, and cellbased bioprinting processes to create a multiscale and multimaterial conduit structure. PC12 nerve cells were shown to be printed with high cell viability (>95%) and to proliferate within the rolled construct at a rate consistent with traditional twodimensional (2D) culture. Light microscopy and scanning electron microscopy (SEM) have also shown encapsulation of cells within the printed alginate gel and an even cell distribution throughout the heterogeneous cellular construct.
    publisherThe American Society of Mechanical Engineers (ASME)
    titleBiofabrication of Multimaterial Three Dimensional Constructs Embedded With Patterned Alginate Strands Encapsulating PC12 Neural Cell Lines
    typeJournal Paper
    journal volume6
    journal issue2
    journal titleJournal of Nanotechnology in Engineering and Medicine
    identifier doi10.1115/1.4031173
    journal fristpage21004
    journal lastpage21004
    identifier eissn1949-2952
    treeJournal of Nanotechnology in Engineering and Medicine:;2015:;volume( 006 ):;issue: 002
    contenttypeFulltext
    DSpace software copyright © 2002-2015  DuraSpace
    نرم افزار کتابخانه دیجیتال "دی اسپیس" فارسی شده توسط یابش برای کتابخانه های ایرانی | تماس با یابش
    yabeshDSpacePersian
     
    DSpace software copyright © 2002-2015  DuraSpace
    نرم افزار کتابخانه دیجیتال "دی اسپیس" فارسی شده توسط یابش برای کتابخانه های ایرانی | تماس با یابش
    yabeshDSpacePersian