An Enhanced One Layer Passive Microfluidic Mixer With an Optimized Lateral Structure With the Dean Effect

Abstract

Topology optimization method is applied to a contraction–expansion structure, based on which a simplified lateral flow structure is generated using the Boolean operation. A new onelayer mixer is then designed by sequentially connecting this lateral structure and bent channels. The mixing efficiency is further optimized via iterations on key geometric parameters associated with the onelayer mixer designed. Numerical results indicate that the optimized mixer has better mixing efficiency than the conventional contraction–expansion mixer for a wide range of the Reynolds number.