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    Computational Study of Hemodynamic Effects of Abnormal E/A Ratio on Left Ventricular Filling

    Source: Journal of Biomechanical Engineering:;2014:;volume( 136 ):;issue: 006::page 61005
    Author:
    Zheng, Xudong
    ,
    Xue, Qian
    ,
    Mittal, Rajat
    DOI: 10.1115/1.4027268
    Publisher: The American Society of Mechanical Engineers (ASME)
    Abstract: Threedimensional numerical simulations are employed to investigate the hemodynamic effects of abnormal E/A ratios on left ventricular filling. The simulations are performed in a simplified geometric model of the left ventricle (LV) in conjunction with a specified endocardial motion. The model has been carefully designed to match the important geometric and flow parameters under the physiological conditions. A wide range of E/A ratios from 0 to infinity is employed with the aim to cover all the possible stages of left ventricle diastolic dysfunction (DD). The effects of abnormal E/A ratios on vortex dynamics, flow propagation velocity, energy consumption as well as flow transport and mixing are extensively discussed. Our results are able to confirm some common findings reported by the previous studies, and also uncover some interesting new features.
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      Computational Study of Hemodynamic Effects of Abnormal E/A Ratio on Left Ventricular Filling

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    http://yetl.yabesh.ir/yetl1/handle/yetl/154016
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    • Journal of Biomechanical Engineering

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    contributor authorZheng, Xudong
    contributor authorXue, Qian
    contributor authorMittal, Rajat
    date accessioned2017-05-09T01:05:27Z
    date available2017-05-09T01:05:27Z
    date issued2014
    identifier issn0148-0731
    identifier otherbio_136_06_061005.pdf
    identifier urihttp://yetl.yabesh.ir/yetl/handle/yetl/154016
    description abstractThreedimensional numerical simulations are employed to investigate the hemodynamic effects of abnormal E/A ratios on left ventricular filling. The simulations are performed in a simplified geometric model of the left ventricle (LV) in conjunction with a specified endocardial motion. The model has been carefully designed to match the important geometric and flow parameters under the physiological conditions. A wide range of E/A ratios from 0 to infinity is employed with the aim to cover all the possible stages of left ventricle diastolic dysfunction (DD). The effects of abnormal E/A ratios on vortex dynamics, flow propagation velocity, energy consumption as well as flow transport and mixing are extensively discussed. Our results are able to confirm some common findings reported by the previous studies, and also uncover some interesting new features.
    publisherThe American Society of Mechanical Engineers (ASME)
    titleComputational Study of Hemodynamic Effects of Abnormal E/A Ratio on Left Ventricular Filling
    typeJournal Paper
    journal volume136
    journal issue6
    journal titleJournal of Biomechanical Engineering
    identifier doi10.1115/1.4027268
    journal fristpage61005
    journal lastpage61005
    identifier eissn1528-8951
    treeJournal of Biomechanical Engineering:;2014:;volume( 136 ):;issue: 006
    contenttypeFulltext
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    DSpace software copyright © 2002-2015  DuraSpace
    نرم افزار کتابخانه دیجیتال "دی اسپیس" فارسی شده توسط یابش برای کتابخانه های ایرانی | تماس با یابش
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