Study of Liquid Metal Based Heating Method for Temperature Gradient Focusing PurposeSource: Journal of Heat Transfer:;2013:;volume( 135 ):;issue: 009::page 91402DOI: 10.1115/1.4024426Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: Temperature gradient focusing (TGF) is a highly efficient focusing technique for the concentration and separation of charged analytes in microfluidic channels. The design of an appropriate temperature gradient is very important for the focusing efficiency. In this study, we proposed a new technique to generate the temperature gradient. This technique utilizes a microchannel filled with liquidmetal as an electrical heater in a microfluidic chip. By applying an electric current, the liquidmetal heater generates Joule heat, forming the temperature gradient in the microchannel. To optimize the temperature gradient and find out the optimal design for the TGF chip, numerical simulations on four typical designs were studied. The results showed that design 1 can provide a best focusing method, which has the largest temperature gradient. For this best design, the temperature is almost linearly distributed along the focusing microchannel. The numerical simulations were then validated both theoretically and experimentally. The following experiment and theoretical analysis on the best design also provide a useful guidance for designing and fabricating the liquidmetal based TGF microchip.
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contributor author | Gao, M. | |
contributor author | Gui, L. | |
contributor author | Liu, J. | |
date accessioned | 2017-05-09T01:00:01Z | |
date available | 2017-05-09T01:00:01Z | |
date issued | 2013 | |
identifier issn | 0022-1481 | |
identifier other | ht_135_09_091402.pdf | |
identifier uri | http://yetl.yabesh.ir/yetl/handle/yetl/152218 | |
description abstract | Temperature gradient focusing (TGF) is a highly efficient focusing technique for the concentration and separation of charged analytes in microfluidic channels. The design of an appropriate temperature gradient is very important for the focusing efficiency. In this study, we proposed a new technique to generate the temperature gradient. This technique utilizes a microchannel filled with liquidmetal as an electrical heater in a microfluidic chip. By applying an electric current, the liquidmetal heater generates Joule heat, forming the temperature gradient in the microchannel. To optimize the temperature gradient and find out the optimal design for the TGF chip, numerical simulations on four typical designs were studied. The results showed that design 1 can provide a best focusing method, which has the largest temperature gradient. For this best design, the temperature is almost linearly distributed along the focusing microchannel. The numerical simulations were then validated both theoretically and experimentally. The following experiment and theoretical analysis on the best design also provide a useful guidance for designing and fabricating the liquidmetal based TGF microchip. | |
publisher | The American Society of Mechanical Engineers (ASME) | |
title | Study of Liquid Metal Based Heating Method for Temperature Gradient Focusing Purpose | |
type | Journal Paper | |
journal volume | 135 | |
journal issue | 9 | |
journal title | Journal of Heat Transfer | |
identifier doi | 10.1115/1.4024426 | |
journal fristpage | 91402 | |
journal lastpage | 91402 | |
identifier eissn | 1528-8943 | |
tree | Journal of Heat Transfer:;2013:;volume( 135 ):;issue: 009 | |
contenttype | Fulltext |