Viscoelastic Material Properties of the Myocardium and Cardiac Jelly in the Looping Chick HeartSource: Journal of Biomechanical Engineering:;2012:;volume( 134 ):;issue: 002::page 24502Author:Jiang Yao
,
Victor D. Varner
,
Lauren L. Brilli
,
Jonathan M. Young
,
Larry A. Taber
,
Renato Perucchio
DOI: 10.1115/1.4005693Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: Accurate material properties of developing embryonic tissues are a crucial factor in studies of the mechanics of morphogenesis. In the present work, we characterize the viscoelastic material properties of the looping heart tube in the chick embryo through nonlinear finite element modeling and microindentation experiments. Both hysteresis and ramp-hold experiments were performed on the intact heart and isolated cardiac jelly (extracellular matrix). An inverse computational method was used to determine the constitutive relations for the myocardium and cardiac jelly. With both layers assumed to be quasilinear viscoelastic, material coefficients for an Ogden type strain-energy density function combined with Prony series of two terms or less were determined by fitting numerical results from a simplified model of a heart segment to experimental data. The experimental and modeling techniques can be applied generally for determining viscoelastic material properties of embryonic tissues.
keyword(s): Density , Viscoelastic materials , Biological tissues , Constitutive equations , Modeling , Stress , Myocardium , Computational methods , Relaxation (Physics) , Materials properties , Force AND Fittings ,
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contributor author | Jiang Yao | |
contributor author | Victor D. Varner | |
contributor author | Lauren L. Brilli | |
contributor author | Jonathan M. Young | |
contributor author | Larry A. Taber | |
contributor author | Renato Perucchio | |
date accessioned | 2017-05-09T00:48:37Z | |
date available | 2017-05-09T00:48:37Z | |
date copyright | February, 2012 | |
date issued | 2012 | |
identifier issn | 0148-0731 | |
identifier other | JBENDY-28990#024502_1.pdf | |
identifier uri | http://yetl.yabesh.ir/yetl/handle/yetl/148292 | |
description abstract | Accurate material properties of developing embryonic tissues are a crucial factor in studies of the mechanics of morphogenesis. In the present work, we characterize the viscoelastic material properties of the looping heart tube in the chick embryo through nonlinear finite element modeling and microindentation experiments. Both hysteresis and ramp-hold experiments were performed on the intact heart and isolated cardiac jelly (extracellular matrix). An inverse computational method was used to determine the constitutive relations for the myocardium and cardiac jelly. With both layers assumed to be quasilinear viscoelastic, material coefficients for an Ogden type strain-energy density function combined with Prony series of two terms or less were determined by fitting numerical results from a simplified model of a heart segment to experimental data. The experimental and modeling techniques can be applied generally for determining viscoelastic material properties of embryonic tissues. | |
publisher | The American Society of Mechanical Engineers (ASME) | |
title | Viscoelastic Material Properties of the Myocardium and Cardiac Jelly in the Looping Chick Heart | |
type | Journal Paper | |
journal volume | 134 | |
journal issue | 2 | |
journal title | Journal of Biomechanical Engineering | |
identifier doi | 10.1115/1.4005693 | |
journal fristpage | 24502 | |
identifier eissn | 1528-8951 | |
keywords | Density | |
keywords | Viscoelastic materials | |
keywords | Biological tissues | |
keywords | Constitutive equations | |
keywords | Modeling | |
keywords | Stress | |
keywords | Myocardium | |
keywords | Computational methods | |
keywords | Relaxation (Physics) | |
keywords | Materials properties | |
keywords | Force AND Fittings | |
tree | Journal of Biomechanical Engineering:;2012:;volume( 134 ):;issue: 002 | |
contenttype | Fulltext |