A Novel Device to Apply Controlled Flexion and Extension to the Rat Knee Following Anterior Cruciate Ligament ReconstructionSource: Journal of Biomechanical Engineering:;2012:;volume( 134 ):;issue: 004::page 41008Author:Mark E. Stasiak
,
Dan Wiznia
,
Michael C. Ciccotti
,
Carl W. Imhauser
,
Peter A. Torzilli
,
Xiang-Hua Deng
,
Scott A. Rodeo
,
Clifford Voigt
,
Saif Alzoobaee
DOI: 10.1115/1.4006341Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: We designed and validated a novel device for applying flexion-extension cycles to a rat knee in an in vivo model of anterior cruciate ligament reconstruction (ACL-R). Our device is intended to simulate rehabilitation motion and exercise post ACL-R to optimize physical rehabilitation treatments for the improved healing of tendon graft ligament reconstructions. The device was validated for repeatability of the knee kinematic motion by measuring the force versus angular rotation response from repeated trials using cadaver rats. The average maximum force required for rotating an ACL reconstructed rat knee through 100 degrees of flexion-extension was 0.4 N with 95% variability for all trials within ±0.1 N.
keyword(s): Motion , Stress , Cycles , Tendons , Anterior cruciate ligament , Knee , Force AND Rotation ,
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| contributor author | Mark E. Stasiak | |
| contributor author | Dan Wiznia | |
| contributor author | Michael C. Ciccotti | |
| contributor author | Carl W. Imhauser | |
| contributor author | Peter A. Torzilli | |
| contributor author | Xiang-Hua Deng | |
| contributor author | Scott A. Rodeo | |
| contributor author | Clifford Voigt | |
| contributor author | Saif Alzoobaee | |
| date accessioned | 2017-05-09T00:48:33Z | |
| date available | 2017-05-09T00:48:33Z | |
| date copyright | April, 2012 | |
| date issued | 2012 | |
| identifier issn | 0148-0731 | |
| identifier other | JBENDY-28992#041008_1.pdf | |
| identifier uri | http://yetl.yabesh.ir/yetl/handle/yetl/148268 | |
| description abstract | We designed and validated a novel device for applying flexion-extension cycles to a rat knee in an in vivo model of anterior cruciate ligament reconstruction (ACL-R). Our device is intended to simulate rehabilitation motion and exercise post ACL-R to optimize physical rehabilitation treatments for the improved healing of tendon graft ligament reconstructions. The device was validated for repeatability of the knee kinematic motion by measuring the force versus angular rotation response from repeated trials using cadaver rats. The average maximum force required for rotating an ACL reconstructed rat knee through 100 degrees of flexion-extension was 0.4 N with 95% variability for all trials within ±0.1 N. | |
| publisher | The American Society of Mechanical Engineers (ASME) | |
| title | A Novel Device to Apply Controlled Flexion and Extension to the Rat Knee Following Anterior Cruciate Ligament Reconstruction | |
| type | Journal Paper | |
| journal volume | 134 | |
| journal issue | 4 | |
| journal title | Journal of Biomechanical Engineering | |
| identifier doi | 10.1115/1.4006341 | |
| journal fristpage | 41008 | |
| identifier eissn | 1528-8951 | |
| keywords | Motion | |
| keywords | Stress | |
| keywords | Cycles | |
| keywords | Tendons | |
| keywords | Anterior cruciate ligament | |
| keywords | Knee | |
| keywords | Force AND Rotation | |
| tree | Journal of Biomechanical Engineering:;2012:;volume( 134 ):;issue: 004 | |
| contenttype | Fulltext |