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    Two-Dimensional Optimization of a Stent for an Aneurysm

    Source: Journal of Medical Devices:;2010:;volume( 004 ):;issue: 002::page 21003
    Author:
    K. Srinivas
    ,
    S. Townsend
    ,
    T. Nakayama
    ,
    T. Yamaguchi
    ,
    M. Ohta
    ,
    C. J. Lee
    ,
    S. Obayashi
    DOI: 10.1115/1.4001861
    Publisher: The American Society of Mechanical Engineers (ASME)
    Abstract: This work attempts to optimize stents that are implanted at the neck of coronary or cerebral aneurysms to effect a flow diversion. A two-dimensional version of the stent, which is a series of struts and gaps placed at the neck, is considered as the first step. Optimization is carried out based on the principles of exploration of design space using reductions in velocity and vorticity in the aneurysm dome as the objective functions. Latin hypercube sampling first develops 30–60 samples of a strut-gap arrangement. Flow past an aneurysm with each of these samples is computed using the commercial software FLUENT and the objective functions evaluated. This is followed by a Kriging procedure that identifies the nondominated solutions to the system, which are the optimized candidates. Three different cases of stents with rectangular or circular struts are considered. It is found that placing struts in the proximal region of the neck gives the best flow diversion.
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      Two-Dimensional Optimization of a Stent for an Aneurysm

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    http://yetl.yabesh.ir/yetl1/handle/yetl/144484
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    contributor authorK. Srinivas
    contributor authorS. Townsend
    contributor authorT. Nakayama
    contributor authorT. Yamaguchi
    contributor authorM. Ohta
    contributor authorC. J. Lee
    contributor authorS. Obayashi
    date accessioned2017-05-09T00:40:08Z
    date available2017-05-09T00:40:08Z
    date copyrightJune, 2010
    date issued2010
    identifier issn1932-6181
    identifier otherJMDOA4-28010#021003_1.pdf
    identifier urihttp://yetl.yabesh.ir/yetl/handle/yetl/144484
    description abstractThis work attempts to optimize stents that are implanted at the neck of coronary or cerebral aneurysms to effect a flow diversion. A two-dimensional version of the stent, which is a series of struts and gaps placed at the neck, is considered as the first step. Optimization is carried out based on the principles of exploration of design space using reductions in velocity and vorticity in the aneurysm dome as the objective functions. Latin hypercube sampling first develops 30–60 samples of a strut-gap arrangement. Flow past an aneurysm with each of these samples is computed using the commercial software FLUENT and the objective functions evaluated. This is followed by a Kriging procedure that identifies the nondominated solutions to the system, which are the optimized candidates. Three different cases of stents with rectangular or circular struts are considered. It is found that placing struts in the proximal region of the neck gives the best flow diversion.
    publisherThe American Society of Mechanical Engineers (ASME)
    titleTwo-Dimensional Optimization of a Stent for an Aneurysm
    typeJournal Paper
    journal volume4
    journal issue2
    journal titleJournal of Medical Devices
    identifier doi10.1115/1.4001861
    journal fristpage21003
    identifier eissn1932-619X
    treeJournal of Medical Devices:;2010:;volume( 004 ):;issue: 002
    contenttypeFulltext
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