YaBeSH Engineering and Technology Library

    • Journals
    • PaperQuest
    • YSE Standards
    • YaBeSH
    • Login
    View Item 
    •   YE&T Library
    • ASME
    • Journal of Biomechanical Engineering
    • View Item
    •   YE&T Library
    • ASME
    • Journal of Biomechanical Engineering
    • View Item
    • All Fields
    • Source Title
    • Year
    • Publisher
    • Title
    • Subject
    • Author
    • DOI
    • ISBN
    Advanced Search
    JavaScript is disabled for your browser. Some features of this site may not work without it.

    Archive

    One-Dimensional Models of the Human Biliary System

    Source: Journal of Biomechanical Engineering:;2007:;volume( 129 ):;issue: 002::page 164
    Author:
    W. G. Li
    ,
    X. Y. Luo
    ,
    A. G. Johnson
    ,
    N. A. Hill
    ,
    N. Bird
    ,
    S. B. Chin
    DOI: 10.1115/1.2472379
    Publisher: The American Society of Mechanical Engineers (ASME)
    Abstract: This paper studies two one-dimensional models to estimate the pressure drop in the normal human biliary system for Reynolds number up to 20. Excessive pressure drop during bile emptying and refilling may result in incomplete bile emptying, leading to stasis and subsequent formation of gallbladder stones. The models were developed following the group’s previous work on the cystic duct using numerical simulations. Using these models, the effects of the biliary system geometry, elastic property of the cystic duct, and bile viscosity on the pressure drop can be studied more efficiently than with full numerical approaches. It was found that the maximum pressure drop occurs during bile emptying immediately after a meal, and is greatly influenced by the viscosity of the bile and the geometric configuration of the cystic duct, i.e., patients with more viscous bile or with a cystic duct containing more baffles or a longer length, have the greatest pressure drop. It is found that the most significant parameter is the diameter of the cystic duct; a 1% decrease in the diameter increases the pressure drop by up to 4.3%. The effects of the baffle height ratio and number of baffles on the pressure drop are reflected in the fact that these effectively change the equivalent diameter and length of the cystic duct. The effect of the Young’s modulus on the pressure drop is important only if it is lower than 400Pa; above this value, a rigid-walled model gives a good estimate of the pressure drop in the system for the parameters studied.
    • Download: (274.9Kb)
    • Show Full MetaData Hide Full MetaData
    • Get RIS
    • Item Order
    • Go To Publisher
    • Price: 5000 Rial
    • Statistics

      One-Dimensional Models of the Human Biliary System

    URI
    http://yetl.yabesh.ir/yetl1/handle/yetl/135276
    Collections
    • Journal of Biomechanical Engineering

    Show full item record

    contributor authorW. G. Li
    contributor authorX. Y. Luo
    contributor authorA. G. Johnson
    contributor authorN. A. Hill
    contributor authorN. Bird
    contributor authorS. B. Chin
    date accessioned2017-05-09T00:22:48Z
    date available2017-05-09T00:22:48Z
    date copyrightApril, 2007
    date issued2007
    identifier issn0148-0731
    identifier otherJBENDY-26680#164_1.pdf
    identifier urihttp://yetl.yabesh.ir/yetl/handle/yetl/135276
    description abstractThis paper studies two one-dimensional models to estimate the pressure drop in the normal human biliary system for Reynolds number up to 20. Excessive pressure drop during bile emptying and refilling may result in incomplete bile emptying, leading to stasis and subsequent formation of gallbladder stones. The models were developed following the group’s previous work on the cystic duct using numerical simulations. Using these models, the effects of the biliary system geometry, elastic property of the cystic duct, and bile viscosity on the pressure drop can be studied more efficiently than with full numerical approaches. It was found that the maximum pressure drop occurs during bile emptying immediately after a meal, and is greatly influenced by the viscosity of the bile and the geometric configuration of the cystic duct, i.e., patients with more viscous bile or with a cystic duct containing more baffles or a longer length, have the greatest pressure drop. It is found that the most significant parameter is the diameter of the cystic duct; a 1% decrease in the diameter increases the pressure drop by up to 4.3%. The effects of the baffle height ratio and number of baffles on the pressure drop are reflected in the fact that these effectively change the equivalent diameter and length of the cystic duct. The effect of the Young’s modulus on the pressure drop is important only if it is lower than 400Pa; above this value, a rigid-walled model gives a good estimate of the pressure drop in the system for the parameters studied.
    publisherThe American Society of Mechanical Engineers (ASME)
    titleOne-Dimensional Models of the Human Biliary System
    typeJournal Paper
    journal volume129
    journal issue2
    journal titleJournal of Biomechanical Engineering
    identifier doi10.1115/1.2472379
    journal fristpage164
    journal lastpage173
    identifier eissn1528-8951
    treeJournal of Biomechanical Engineering:;2007:;volume( 129 ):;issue: 002
    contenttypeFulltext
    DSpace software copyright © 2002-2015  DuraSpace
    نرم افزار کتابخانه دیجیتال "دی اسپیس" فارسی شده توسط یابش برای کتابخانه های ایرانی | تماس با یابش
    yabeshDSpacePersian
     
    DSpace software copyright © 2002-2015  DuraSpace
    نرم افزار کتابخانه دیجیتال "دی اسپیس" فارسی شده توسط یابش برای کتابخانه های ایرانی | تماس با یابش
    yabeshDSpacePersian