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    A 3D Computational Simulation of Fracture Callus Formation: Influence of the Stiffness of the External Fixator

    Source: Journal of Biomechanical Engineering:;2006:;volume( 128 ):;issue: 003::page 290
    Author:
    M. J. Gómez-Benito
    ,
    J. H. Kuiper
    ,
    M. Doblaré
    ,
    J. M. García-Aznar
    DOI: 10.1115/1.2187045
    Publisher: The American Society of Mechanical Engineers (ASME)
    Abstract: The stiffness of the external fixation highly influences the fracture healing pattern. In this work we study this aspect by means of a finite element model of a simple transverse mid-diaphyseal fracture of an ovine metatarsus fixed with a bilateral external fixator. In order to simulate the regenerative process, a previously developed mechanobiological model of bone fracture healing was implemented in three dimensions. This model is able to simulate tissue differentiation, bone regeneration, and callus growth. A physiological load of 500N was applied and three different stiffnesses of the external fixator were simulated (2300, 1725, and 1150N∕mm). The interfragmentary strain and load sharing mechanism between bone and the external fixator were compared to those recorded in previous experimental works. The effects of the stiffness on the callus shape and tissue distributions in the fracture site were also analyzed. We predicted that a lower stiffness of the fixator delays fracture healing and causes a larger callus, in correspondence to well-documented clinical observations.
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      A 3D Computational Simulation of Fracture Callus Formation: Influence of the Stiffness of the External Fixator

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    http://yetl.yabesh.ir/yetl1/handle/yetl/133192
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    • Journal of Biomechanical Engineering

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    contributor authorM. J. Gómez-Benito
    contributor authorJ. H. Kuiper
    contributor authorM. Doblaré
    contributor authorJ. M. García-Aznar
    date accessioned2017-05-09T00:18:56Z
    date available2017-05-09T00:18:56Z
    date copyrightJune, 2006
    date issued2006
    identifier issn0148-0731
    identifier otherJBENDY-26597#290_1.pdf
    identifier urihttp://yetl.yabesh.ir/yetl/handle/yetl/133192
    description abstractThe stiffness of the external fixation highly influences the fracture healing pattern. In this work we study this aspect by means of a finite element model of a simple transverse mid-diaphyseal fracture of an ovine metatarsus fixed with a bilateral external fixator. In order to simulate the regenerative process, a previously developed mechanobiological model of bone fracture healing was implemented in three dimensions. This model is able to simulate tissue differentiation, bone regeneration, and callus growth. A physiological load of 500N was applied and three different stiffnesses of the external fixator were simulated (2300, 1725, and 1150N∕mm). The interfragmentary strain and load sharing mechanism between bone and the external fixator were compared to those recorded in previous experimental works. The effects of the stiffness on the callus shape and tissue distributions in the fracture site were also analyzed. We predicted that a lower stiffness of the fixator delays fracture healing and causes a larger callus, in correspondence to well-documented clinical observations.
    publisherThe American Society of Mechanical Engineers (ASME)
    titleA 3D Computational Simulation of Fracture Callus Formation: Influence of the Stiffness of the External Fixator
    typeJournal Paper
    journal volume128
    journal issue3
    journal titleJournal of Biomechanical Engineering
    identifier doi10.1115/1.2187045
    journal fristpage290
    journal lastpage299
    identifier eissn1528-8951
    treeJournal of Biomechanical Engineering:;2006:;volume( 128 ):;issue: 003
    contenttypeFulltext
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    DSpace software copyright © 2002-2015  DuraSpace
    نرم افزار کتابخانه دیجیتال "دی اسپیس" فارسی شده توسط یابش برای کتابخانه های ایرانی | تماس با یابش
    yabeshDSpacePersian