Experimental Verification of the Roles of Intrinsic Matrix Viscoelasticity and Tension-Compression Nonlinearity in the Biphasic Response of CartilageSource: Journal of Biomechanical Engineering:;2003:;volume( 125 ):;issue: 001::page 84DOI: 10.1115/1.1531656Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: A biphasic-CLE-QLV model proposed in our recent study [2001, J. Biomech. Eng., 123 , pp. 410–417] extended the biphasic theory of Mow et al. [1980, J. Biomech. Eng., 102 , pp. 73–84] to include both tension-compression nonlinearity and intrinsic viscoelasticity of the cartilage solid matrix by incorporating it with the conewise linear elasticity (CLE) model [1995, J. Elasticity, 37 , pp. 1–38] and the quasi-linear viscoelasticity (QLV) model [Biomechanics: Its foundations and objectives, Prentice Hall, Englewood Cliffs, 1972]. This model demonstrates that a simultaneous prediction of compression and tension experiments of articular cartilage, under stress-relaxation and dynamic loading, can be achieved when properly taking into account both flow-dependent and flow-independent viscoelastic effects, as well as tension-compression nonlinearity. The objective of this study is to directly test this biphasic-CLE-QLV model against experimental data from unconfined compression stress-relaxation tests at slow and fast strain rates as well as dynamic loading. Twelve full-thickness cartilage cylindrical plugs were harvested from six bovine glenohumeral joints and multiple confined and unconfined compression stress-relaxation tests were performed on each specimen. The material properties of specimens were determined by curve-fitting the experimental results from the confined and unconfined compression stress relaxation tests. The findings of this study demonstrate that the biphasic-CLE-QLV model is able to describe the strain-rate-dependent mechanical behaviors of articular cartilage in unconfined compression as attested by good agreements between experimental and theoretical curvefits (r2=0.966±0.032 for testing at slow strain rate; r2=0.998±0.002 for testing at fast strain rate) and predictions of the dynamic response (r2=0.91±0.06). This experimental study also provides supporting evidence for the hypothesis that both tension-compression nonlinearity and intrinsic viscoelasticity of the solid matrix of cartilage are necessary for modeling the transient and equilibrium responses of this tissue in tension and compression. Furthermore, the biphasic-CLE-QLV model can produce better predictions of the dynamic modulus of cartilage in unconfined dynamic compression than the biphasic-CLE and biphasic poroviscoelastic models, indicating that intrinsic viscoelasticity and tension-compression nonlinearity of articular cartilage may play important roles in the load-support mechanism of cartilage under physiologic loading.
keyword(s): Stress , Viscoelasticity , Compression , Tension , Cartilage , Equilibrium (Physics) , Relaxation (Physics) , Fittings , Biological tissues , Materials properties AND Testing ,
|
Collections
Show full item record
contributor author | Chun-Yuh Huang | |
contributor author | Michael A. Soltz | |
contributor author | Monika Kopacz | |
contributor author | Van C. Mow | |
contributor author | Gerard A. Ateshian | |
date accessioned | 2017-05-09T00:09:34Z | |
date available | 2017-05-09T00:09:34Z | |
date copyright | February, 2003 | |
date issued | 2003 | |
identifier issn | 0148-0731 | |
identifier other | JBENDY-26293#84_1.pdf | |
identifier uri | http://yetl.yabesh.ir/yetl/handle/yetl/128023 | |
description abstract | A biphasic-CLE-QLV model proposed in our recent study [2001, J. Biomech. Eng., 123 , pp. 410–417] extended the biphasic theory of Mow et al. [1980, J. Biomech. Eng., 102 , pp. 73–84] to include both tension-compression nonlinearity and intrinsic viscoelasticity of the cartilage solid matrix by incorporating it with the conewise linear elasticity (CLE) model [1995, J. Elasticity, 37 , pp. 1–38] and the quasi-linear viscoelasticity (QLV) model [Biomechanics: Its foundations and objectives, Prentice Hall, Englewood Cliffs, 1972]. This model demonstrates that a simultaneous prediction of compression and tension experiments of articular cartilage, under stress-relaxation and dynamic loading, can be achieved when properly taking into account both flow-dependent and flow-independent viscoelastic effects, as well as tension-compression nonlinearity. The objective of this study is to directly test this biphasic-CLE-QLV model against experimental data from unconfined compression stress-relaxation tests at slow and fast strain rates as well as dynamic loading. Twelve full-thickness cartilage cylindrical plugs were harvested from six bovine glenohumeral joints and multiple confined and unconfined compression stress-relaxation tests were performed on each specimen. The material properties of specimens were determined by curve-fitting the experimental results from the confined and unconfined compression stress relaxation tests. The findings of this study demonstrate that the biphasic-CLE-QLV model is able to describe the strain-rate-dependent mechanical behaviors of articular cartilage in unconfined compression as attested by good agreements between experimental and theoretical curvefits (r2=0.966±0.032 for testing at slow strain rate; r2=0.998±0.002 for testing at fast strain rate) and predictions of the dynamic response (r2=0.91±0.06). This experimental study also provides supporting evidence for the hypothesis that both tension-compression nonlinearity and intrinsic viscoelasticity of the solid matrix of cartilage are necessary for modeling the transient and equilibrium responses of this tissue in tension and compression. Furthermore, the biphasic-CLE-QLV model can produce better predictions of the dynamic modulus of cartilage in unconfined dynamic compression than the biphasic-CLE and biphasic poroviscoelastic models, indicating that intrinsic viscoelasticity and tension-compression nonlinearity of articular cartilage may play important roles in the load-support mechanism of cartilage under physiologic loading. | |
publisher | The American Society of Mechanical Engineers (ASME) | |
title | Experimental Verification of the Roles of Intrinsic Matrix Viscoelasticity and Tension-Compression Nonlinearity in the Biphasic Response of Cartilage | |
type | Journal Paper | |
journal volume | 125 | |
journal issue | 1 | |
journal title | Journal of Biomechanical Engineering | |
identifier doi | 10.1115/1.1531656 | |
journal fristpage | 84 | |
journal lastpage | 93 | |
identifier eissn | 1528-8951 | |
keywords | Stress | |
keywords | Viscoelasticity | |
keywords | Compression | |
keywords | Tension | |
keywords | Cartilage | |
keywords | Equilibrium (Physics) | |
keywords | Relaxation (Physics) | |
keywords | Fittings | |
keywords | Biological tissues | |
keywords | Materials properties AND Testing | |
tree | Journal of Biomechanical Engineering:;2003:;volume( 125 ):;issue: 001 | |
contenttype | Fulltext |