Self-sealing, Large Bore Arterial Punctures: A Counterintuitive New PhenomenonSource: Journal of Biomechanical Engineering:;2002:;volume( 124 ):;issue: 004::page 342Author:Blayne A. Roeder
,
ASME Student Mem.
,
Charles F. Babbs
,
William E. Schoenlein
,
Klod Kokini
,
ASME Mem.
,
Farshid Sadeghi
,
ASME Mem.
DOI: 10.1115/1.1488935Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: The human femoral artery can bleed dangerously following the removal of a catheter during cardiac catheterization. In this study, a modified technique of needle insertion, simply inserting the needle bevel-down instead of the standard bevel-up approach, was tested as a means to reduce bleeding after catheter removal. Large bore needle punctures were made in surgically exposed arteries of anesthetized pigs using either a standard technique (45 degree approach, bevel up) or a modified technique (25 degree approach, bevel down). For half the punctures, topical phenylephrine solution (1 mg/ml) was applied to the adventitia of the artery to cause constriction. Median bleeding rates were reduced from 81 to less than 1 ml/min/100 mmHg intraluminal pressure by the modified technique with application of phenylephrine. In most cases zero bleeding, that is self-sealing, of the arteries occurred. It is postulated that a flap-valve of tissue created by the modified technique produced this self-sealing behavior. Sophisticated modeling studies are needed to fully understand this new phenomenon.
keyword(s): Pressure , Sealing (Process) , Biological tissues , Valves , Catheters , needles AND Surgery ,
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contributor author | Blayne A. Roeder | |
contributor author | ASME Student Mem. | |
contributor author | Charles F. Babbs | |
contributor author | William E. Schoenlein | |
contributor author | Klod Kokini | |
contributor author | ASME Mem. | |
contributor author | Farshid Sadeghi | |
contributor author | ASME Mem. | |
date accessioned | 2017-05-09T00:06:48Z | |
date available | 2017-05-09T00:06:48Z | |
date copyright | August, 2002 | |
date issued | 2002 | |
identifier issn | 0148-0731 | |
identifier other | JBENDY-26256#342_1.pdf | |
identifier uri | http://yetl.yabesh.ir/yetl/handle/yetl/126371 | |
description abstract | The human femoral artery can bleed dangerously following the removal of a catheter during cardiac catheterization. In this study, a modified technique of needle insertion, simply inserting the needle bevel-down instead of the standard bevel-up approach, was tested as a means to reduce bleeding after catheter removal. Large bore needle punctures were made in surgically exposed arteries of anesthetized pigs using either a standard technique (45 degree approach, bevel up) or a modified technique (25 degree approach, bevel down). For half the punctures, topical phenylephrine solution (1 mg/ml) was applied to the adventitia of the artery to cause constriction. Median bleeding rates were reduced from 81 to less than 1 ml/min/100 mmHg intraluminal pressure by the modified technique with application of phenylephrine. In most cases zero bleeding, that is self-sealing, of the arteries occurred. It is postulated that a flap-valve of tissue created by the modified technique produced this self-sealing behavior. Sophisticated modeling studies are needed to fully understand this new phenomenon. | |
publisher | The American Society of Mechanical Engineers (ASME) | |
title | Self-sealing, Large Bore Arterial Punctures: A Counterintuitive New Phenomenon | |
type | Journal Paper | |
journal volume | 124 | |
journal issue | 4 | |
journal title | Journal of Biomechanical Engineering | |
identifier doi | 10.1115/1.1488935 | |
journal fristpage | 342 | |
journal lastpage | 346 | |
identifier eissn | 1528-8951 | |
keywords | Pressure | |
keywords | Sealing (Process) | |
keywords | Biological tissues | |
keywords | Valves | |
keywords | Catheters | |
keywords | needles AND Surgery | |
tree | Journal of Biomechanical Engineering:;2002:;volume( 124 ):;issue: 004 | |
contenttype | Fulltext |