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    Self-sealing, Large Bore Arterial Punctures: A Counterintuitive New Phenomenon

    Source: Journal of Biomechanical Engineering:;2002:;volume( 124 ):;issue: 004::page 342
    Author:
    Blayne A. Roeder
    ,
    ASME Student Mem.
    ,
    Charles F. Babbs
    ,
    William E. Schoenlein
    ,
    Klod Kokini
    ,
    ASME Mem.
    ,
    Farshid Sadeghi
    ,
    ASME Mem.
    DOI: 10.1115/1.1488935
    Publisher: The American Society of Mechanical Engineers (ASME)
    Abstract: The human femoral artery can bleed dangerously following the removal of a catheter during cardiac catheterization. In this study, a modified technique of needle insertion, simply inserting the needle bevel-down instead of the standard bevel-up approach, was tested as a means to reduce bleeding after catheter removal. Large bore needle punctures were made in surgically exposed arteries of anesthetized pigs using either a standard technique (45 degree approach, bevel up) or a modified technique (25 degree approach, bevel down). For half the punctures, topical phenylephrine solution (1 mg/ml) was applied to the adventitia of the artery to cause constriction. Median bleeding rates were reduced from 81 to less than 1 ml/min/100 mmHg intraluminal pressure by the modified technique with application of phenylephrine. In most cases zero bleeding, that is self-sealing, of the arteries occurred. It is postulated that a flap-valve of tissue created by the modified technique produced this self-sealing behavior. Sophisticated modeling studies are needed to fully understand this new phenomenon.
    keyword(s): Pressure , Sealing (Process) , Biological tissues , Valves , Catheters , needles AND Surgery ,
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      Self-sealing, Large Bore Arterial Punctures: A Counterintuitive New Phenomenon

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    http://yetl.yabesh.ir/yetl1/handle/yetl/126371
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    • Journal of Biomechanical Engineering

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    contributor authorBlayne A. Roeder
    contributor authorASME Student Mem.
    contributor authorCharles F. Babbs
    contributor authorWilliam E. Schoenlein
    contributor authorKlod Kokini
    contributor authorASME Mem.
    contributor authorFarshid Sadeghi
    contributor authorASME Mem.
    date accessioned2017-05-09T00:06:48Z
    date available2017-05-09T00:06:48Z
    date copyrightAugust, 2002
    date issued2002
    identifier issn0148-0731
    identifier otherJBENDY-26256#342_1.pdf
    identifier urihttp://yetl.yabesh.ir/yetl/handle/yetl/126371
    description abstractThe human femoral artery can bleed dangerously following the removal of a catheter during cardiac catheterization. In this study, a modified technique of needle insertion, simply inserting the needle bevel-down instead of the standard bevel-up approach, was tested as a means to reduce bleeding after catheter removal. Large bore needle punctures were made in surgically exposed arteries of anesthetized pigs using either a standard technique (45 degree approach, bevel up) or a modified technique (25 degree approach, bevel down). For half the punctures, topical phenylephrine solution (1 mg/ml) was applied to the adventitia of the artery to cause constriction. Median bleeding rates were reduced from 81 to less than 1 ml/min/100 mmHg intraluminal pressure by the modified technique with application of phenylephrine. In most cases zero bleeding, that is self-sealing, of the arteries occurred. It is postulated that a flap-valve of tissue created by the modified technique produced this self-sealing behavior. Sophisticated modeling studies are needed to fully understand this new phenomenon.
    publisherThe American Society of Mechanical Engineers (ASME)
    titleSelf-sealing, Large Bore Arterial Punctures: A Counterintuitive New Phenomenon
    typeJournal Paper
    journal volume124
    journal issue4
    journal titleJournal of Biomechanical Engineering
    identifier doi10.1115/1.1488935
    journal fristpage342
    journal lastpage346
    identifier eissn1528-8951
    keywordsPressure
    keywordsSealing (Process)
    keywordsBiological tissues
    keywordsValves
    keywordsCatheters
    keywordsneedles AND Surgery
    treeJournal of Biomechanical Engineering:;2002:;volume( 124 ):;issue: 004
    contenttypeFulltext
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    DSpace software copyright © 2002-2015  DuraSpace
    نرم افزار کتابخانه دیجیتال "دی اسپیس" فارسی شده توسط یابش برای کتابخانه های ایرانی | تماس با یابش
    yabeshDSpacePersian