Flow Structure and Particle Transport in a Triple Bifurcation Airway Model1

Abstract

Considering steady laminar incompressible flow in a triple bifurcation, which represents generations three to six of the human respiratory system, air flow fields and micron-particle transport have been simulated for several combinations of relatively high and low inlet Reynolds and Stokes numbers. While the upstream bifurcations are hardly affected by the third bifurcation, complex air and particle flow fields occur in the daughter tubes leading to the third dividers. Variations in Reynolds number, 500≤Re≤2000, and Stokes number, 0.04≤St≤0.12, cause locally changing vortical air flows as well as irregular particle motions. Preferential concentration of particles can be induced by the secondary vortical flow in the tubes when the inlet Reynolds number is high enough. The air and particle velocity profiles in the third daughter tubes are still quite different from those in the upstream tubes, which indicates that additional downstream effects are possible. This work may contribute to respiratory dose estimation in health risk assessment studies, as well as the analyses of drug aerosol delivery.