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    A Method to Study Intracellular Ice Nucleation

    Source: Journal of Biomechanical Engineering:;1998:;volume( 120 ):;issue: 001::page 27
    Author:
    K. Tatsutani
    ,
    B. Rubinsky
    DOI: 10.1115/1.2834302
    Publisher: The American Society of Mechanical Engineers (ASME)
    Abstract: The thermodynamics of intracellular ice nucleation are important in low-temperature biology for understanding and controlling the process of cell destruction by freezing. We have developed a new apparatus and technique for studying the physics of intracellular ice nucleation. Employing the principle of directional solidification in conjunction with light microscopy, we can generate information on the temperature at which ice nucleates intracellularly as a function of the thermal history the cells experience. The methodology is introduced, and results with primary prostatic cancer cells are described.
    keyword(s): Nucleation (Physics) , Ice , Low temperature , Solidification , Microscopy , Cancer , Physics , Thermodynamics , Temperature AND Freezing ,
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      A Method to Study Intracellular Ice Nucleation

    URI
    http://yetl.yabesh.ir/yetl1/handle/yetl/120110
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    • Journal of Biomechanical Engineering

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    contributor authorK. Tatsutani
    contributor authorB. Rubinsky
    date accessioned2017-05-08T23:56:03Z
    date available2017-05-08T23:56:03Z
    date copyrightFebruary, 1998
    date issued1998
    identifier issn0148-0731
    identifier otherJBENDY-25986#27_1.pdf
    identifier urihttp://yetl.yabesh.ir/yetl/handle/yetl/120110
    description abstractThe thermodynamics of intracellular ice nucleation are important in low-temperature biology for understanding and controlling the process of cell destruction by freezing. We have developed a new apparatus and technique for studying the physics of intracellular ice nucleation. Employing the principle of directional solidification in conjunction with light microscopy, we can generate information on the temperature at which ice nucleates intracellularly as a function of the thermal history the cells experience. The methodology is introduced, and results with primary prostatic cancer cells are described.
    publisherThe American Society of Mechanical Engineers (ASME)
    titleA Method to Study Intracellular Ice Nucleation
    typeJournal Paper
    journal volume120
    journal issue1
    journal titleJournal of Biomechanical Engineering
    identifier doi10.1115/1.2834302
    journal fristpage27
    journal lastpage31
    identifier eissn1528-8951
    keywordsNucleation (Physics)
    keywordsIce
    keywordsLow temperature
    keywordsSolidification
    keywordsMicroscopy
    keywordsCancer
    keywordsPhysics
    keywordsThermodynamics
    keywordsTemperature AND Freezing
    treeJournal of Biomechanical Engineering:;1998:;volume( 120 ):;issue: 001
    contenttypeFulltext
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