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    The Effect of Angle and Flow Rate Upon Hemodynamics in Distal Vascular Graft Anastomoses: A Numerical Model Study

    Source: Journal of Biomechanical Engineering:;1994:;volume( 116 ):;issue: 003::page 331
    Author:
    Ding-Yu Fei
    ,
    Stanley E. Rittgers
    ,
    James D. Thomas
    DOI: 10.1115/1.2895739
    Publisher: The American Society of Mechanical Engineers (ASME)
    Abstract: Flow in distal end-to-side anastomoses of iliofemoral artery bypass grafts was simulated using a steady flow, three-dimensional numerical model. With the proximal artery occluded, anastomotic angles were varied over 20, 30, 40, 45, 50, 60 and 70 deg while the inlet Reynolds numbers were 100 and 205. Fully developed flow in the graft became somewhat skewed toward the inner wall with increasing angle for both Reynolds numbers. Separated flow regions were seen along the inner arterial wall (toe region) for angles ≥ 60 deg at Re = 100 and for angles ≥ 45 deg at Re = 205 while a stagnation point existed along the outer arterial wall (floor region) for all cases which moved downstream relative to the toe of the anastomosis with decreasing angles. Normalized shear rates (NSR) along the arterial wall varied widely throughout the anastomotic region with negative values seen in the separation zones and upstream of the stagnation points which increased in magnitude with angle. The NSR increased with distance downstream of the stagnation point and with magnitudes which increased with the angle. Compared with observations from chronic in vivo studies, these results appear to support the hypothesis of greater intimal hyperplasia occurring in regions of low fluid shear.
    keyword(s): Flow (Dynamics) , Computer simulation , Hemodynamics , Reynolds number , Shear (Mechanics) , Separation (Technology) AND Fluids ,
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      The Effect of Angle and Flow Rate Upon Hemodynamics in Distal Vascular Graft Anastomoses: A Numerical Model Study

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    http://yetl.yabesh.ir/yetl1/handle/yetl/113247
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    • Journal of Biomechanical Engineering

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    contributor authorDing-Yu Fei
    contributor authorStanley E. Rittgers
    contributor authorJames D. Thomas
    date accessioned2017-05-08T23:43:37Z
    date available2017-05-08T23:43:37Z
    date copyrightAugust, 1994
    date issued1994
    identifier issn0148-0731
    identifier otherJBENDY-25941#331_1.pdf
    identifier urihttp://yetl.yabesh.ir/yetl/handle/yetl/113247
    description abstractFlow in distal end-to-side anastomoses of iliofemoral artery bypass grafts was simulated using a steady flow, three-dimensional numerical model. With the proximal artery occluded, anastomotic angles were varied over 20, 30, 40, 45, 50, 60 and 70 deg while the inlet Reynolds numbers were 100 and 205. Fully developed flow in the graft became somewhat skewed toward the inner wall with increasing angle for both Reynolds numbers. Separated flow regions were seen along the inner arterial wall (toe region) for angles ≥ 60 deg at Re = 100 and for angles ≥ 45 deg at Re = 205 while a stagnation point existed along the outer arterial wall (floor region) for all cases which moved downstream relative to the toe of the anastomosis with decreasing angles. Normalized shear rates (NSR) along the arterial wall varied widely throughout the anastomotic region with negative values seen in the separation zones and upstream of the stagnation points which increased in magnitude with angle. The NSR increased with distance downstream of the stagnation point and with magnitudes which increased with the angle. Compared with observations from chronic in vivo studies, these results appear to support the hypothesis of greater intimal hyperplasia occurring in regions of low fluid shear.
    publisherThe American Society of Mechanical Engineers (ASME)
    titleThe Effect of Angle and Flow Rate Upon Hemodynamics in Distal Vascular Graft Anastomoses: A Numerical Model Study
    typeJournal Paper
    journal volume116
    journal issue3
    journal titleJournal of Biomechanical Engineering
    identifier doi10.1115/1.2895739
    journal fristpage331
    journal lastpage336
    identifier eissn1528-8951
    keywordsFlow (Dynamics)
    keywordsComputer simulation
    keywordsHemodynamics
    keywordsReynolds number
    keywordsShear (Mechanics)
    keywordsSeparation (Technology) AND Fluids
    treeJournal of Biomechanical Engineering:;1994:;volume( 116 ):;issue: 003
    contenttypeFulltext
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