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    A Sensitivity Analysis of the Thermal Pulse Decay Method for Measurement of Local Tissue Conductivity and Blood Perfusion

    Source: Journal of Biomechanical Engineering:;1986:;volume( 108 ):;issue: 001::page 54
    Author:
    H. Arkin
    ,
    K. R. Holmes
    ,
    M. M. Chen
    DOI: 10.1115/1.3138580
    Publisher: The American Society of Mechanical Engineers (ASME)
    Abstract: The T hermal P ulse D ecay (TPD) method for the determination of local tissue thermal conductivity and blood perfusion rate is based on a comparison of measured with theoretically calculated temperatures. A sensitivity analysis of the theoretical model is performed. This analysis supports the establishment of an experimental protocol which reduces the measurement errors: An “optimal” measurement time inverval for typical perfusion rates (up to 6 mL/mL/min) was found to be between 3 and 11 s after the heat pulse is turned off. Within this interval, the maximum error in determination of tissue conductivity and blood perfusion caused by experimental measurement errors is expected not to exceed 5 percent. The presently chosen pulse duration of 3 s is in agreement with the analysis as a good compromise between accuracy and excessive tissue heating.
    keyword(s): Biological tissues , Blood , Conductivity , Sensitivity analysis , Errors , Heating , Heat , Temperature AND Thermal conductivity ,
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      A Sensitivity Analysis of the Thermal Pulse Decay Method for Measurement of Local Tissue Conductivity and Blood Perfusion

    URI
    http://yetl.yabesh.ir/yetl1/handle/yetl/100933
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    • Journal of Biomechanical Engineering

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    contributor authorH. Arkin
    contributor authorK. R. Holmes
    contributor authorM. M. Chen
    date accessioned2017-05-08T23:22:08Z
    date available2017-05-08T23:22:08Z
    date copyrightFebruary, 1986
    date issued1986
    identifier issn0148-0731
    identifier otherJBENDY-25810#54_1.pdf
    identifier urihttp://yetl.yabesh.ir/yetl/handle/yetl/100933
    description abstractThe T hermal P ulse D ecay (TPD) method for the determination of local tissue thermal conductivity and blood perfusion rate is based on a comparison of measured with theoretically calculated temperatures. A sensitivity analysis of the theoretical model is performed. This analysis supports the establishment of an experimental protocol which reduces the measurement errors: An “optimal” measurement time inverval for typical perfusion rates (up to 6 mL/mL/min) was found to be between 3 and 11 s after the heat pulse is turned off. Within this interval, the maximum error in determination of tissue conductivity and blood perfusion caused by experimental measurement errors is expected not to exceed 5 percent. The presently chosen pulse duration of 3 s is in agreement with the analysis as a good compromise between accuracy and excessive tissue heating.
    publisherThe American Society of Mechanical Engineers (ASME)
    titleA Sensitivity Analysis of the Thermal Pulse Decay Method for Measurement of Local Tissue Conductivity and Blood Perfusion
    typeJournal Paper
    journal volume108
    journal issue1
    journal titleJournal of Biomechanical Engineering
    identifier doi10.1115/1.3138580
    journal fristpage54
    journal lastpage58
    identifier eissn1528-8951
    keywordsBiological tissues
    keywordsBlood
    keywordsConductivity
    keywordsSensitivity analysis
    keywordsErrors
    keywordsHeating
    keywordsHeat
    keywordsTemperature AND Thermal conductivity
    treeJournal of Biomechanical Engineering:;1986:;volume( 108 ):;issue: 001
    contenttypeFulltext
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