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Methods to Prepare Perfusion Fixed Cardiac Specimens for Multimodal Imaging: The Use of Formalin and Agar Gels
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: Recent advances in cardiac imaging have resulted in a growing understanding of both the form and function of the heart in vivo. Currently, the primary modalities for cardiac imaging are (1) ...
Simultaneous In Vivo Assessment of Contractile Properties and Electromyographic (EMG) Activities in a Knock-Out Mouse Model of Myotonic Dystrophy
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: Myotonic dystrophy is a dominantly inherited disorder characterized by myotonia and delayed muscle relaxation due to repetitive action potentials in the muscle fibers (hyperexcitability). In this ...
A Novel Ex Vivo Heart Model for the Assessment of Cardiac Pacing Systems
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: Background: Advances in endocardial device design have been limited by the inability to visualize the device-tissue interface. The purpose of this study was to assess the validity of an isolated ...
Development of an Endocardial Cryoablation Catheter for Concomitant Delivery of Cryogenic Treatment and Adjuvants
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: This paper presents the preliminary development of a novel cryoablation catheter for the delivery of cryo-energy and complimentary pharmacological agents selected to improve lesion formation. The ...
Variations in Human Cardiac Vein Anatomies: Direct Mapping Within Fixed Hearts and Digital Reconstructions
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: It is important to identify and understand variations in the anatomy of the human cardiac venous system in order to best develop and then use minimally invasive cardiac devices. Hence, anatomical ...
A Device and Methodology for Continuous Hypothermic Perfusion of Explanted Large Mammalian Hearts, Followed by In Vitro Langendorff Reanimation: Pilot Studies
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: The current methodologies of clinical heart transplantation limit the ischemic window to 4–6 h. Periods longer than this can induce dysfunction in the organ and can lead to increased patient ...
High Capacity Implantable Data Recorders: System Design and Experience in Canines and Denning Black Bears
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: Background: Implantable medical devices have increasingly large capacities for storing patient data as a diagnostic aid and to allow patient monitoring. Although these devices can store a significant ...
Measurement of Impact Loads Applied to an Implanted Drug Pump Connector in a Porcine Cadaver Specimen
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: Anecdotal and documented reports from both patients and doctors have described unanticipated breaks in connections between implanted catheters and drug pumps. In extreme cases, such disconnections ...
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