Abstract: The increasing importance of life science in all engineering is prompting departments in the traditional engineering disciplines to offer life science as part of their curricula. Students who ...

Abstract: Mechanical forces have been widely recognized to play an important role in the pathogenesis of atherosclerosis. Since coronary arterial motion modulates both vessel wall mechanics and fluid ...

Abstract: A variety of shear rate measures have been calculated from hemodynamic data obtained by laser Doppler anemometry in flow-through casts of human aortic bifurcations. Included are measures sensitive ...

Abstract: A realistically compliant flow-through cast of a human aortic bifurcation was perfused with two almost identical physiological flow waves differing in pulsatile frequency. Near-wall fluid velocities ...

Abstract: Background. Temporal variations in shear stress have been suggested to affect endothelial cell biology. To better quantify the range of dynamic shear forces that occur in vivo, the frequency ...

Abstract: Background. In vivo experimentation is the most realistic approach for exploring the vascular biological response to the hemodynamic stresses that are present in life. Post-mortem vascular casting ...

Abstract: The detailed geometry of atherosclerosis-prone vascular segments may influence their susceptibility by mediating local hemodynamics. An appreciation of the role of specific geometric variables is ...

Abstract: Atherosclerotic plaques are distributed differently in the aortic arches of C57BL/6 (B6) and 129/SvEv (129) apolipoprotein E (apoE)-deficient mice. It is now recognized that hemodynamic wall shear ...