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RISAssociation Between Resistance to Cerebrospinal Fluid Flow Near the Foramen Magnum and Cough-Associated Headache in Adult Chiari Malformation Type I
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: Cough-associated headaches (CAHs) are thought to be distinctive for Chiari malformation type I (CMI) patients and have been shown to be related to the motion of cerebrospinal fluid (CSF) near the foramen magnum (FM). We ...
Transition to Turbulence Downstream of a Stenosis for Whole Blood and a Newtonian Analog Under Steady Flow Conditions
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: Blood, a multiphase fluid comprised of plasma, blood cells, and platelets, is known to exhibit a shear-thinning behavior at low shear rates and near-Newtonian behavior at higher shear rates. However, less is known about ...
Characterization of Transition to Turbulence for Blood in a Straight Pipe Under Steady Flow Conditions
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: Blood is a complex fluid that, among other things, has been established to behave as a shear thinning, nonNewtonian fluid when exposed to low shear rates (SR). Many hemodynamic investigations use a Newtonian fluid to ...
Surface Strains of Porcine Tricuspid Valve Septal Leaflets Measured in Ex Vivo Beating Hearts
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: Quantification of the tricuspid valve (TV) leaflets mechanical strain is important in order to understand valve pathophysiology and to develop effective treatment strategies. Many of the traditional methods used to dynamically ...
Regional Quantification of Brain Tissue Strain Using Displacement-Encoding With Stimulated Echoes Magnetic Resonance Imaging
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: Intrinsic cardiac-induced deformation of brain tissue is thought to be important in the pathophysiology of various neurological disorders. In this study, we evaluated the feasibility of utilizing displacement encoding with ...
Impact of Blood Rheology on Transition to Turbulence and Wall Vibration Downstream of a Stenosis
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: Previous experimental flow studies have demonstrated a delay (∼20%) in transition to turbulence for whole blood compared to a Newtonian analog fluid in both a straight pipe and eccentric stenosis model with ridged walls. ...
Characterization of the Discrepancies Between Four Dimensional Phase Contrast Magnetic Resonance Imaging and In Silico Simulations of Cerebrospinal Fluid Dynamics
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: The purpose of the present study was to compare subjectspecific magnetic resonance imaging (MRI)based computational fluid dynamics (CFD) simulations with timeresolved threedirectional (3D) velocityencoded phasecontrast MRI ...
Cerebrospinal Fluid Flow Impedance is Elevated in Type I Chiari Malformation
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: Diagnosis of Type I Chiari malformation (CMI) is difficult because the most commonly used diagnostic criterion, cerebellar tonsillar herniation (CTH) greater than 3–5 mm past the foramen magnum, has been found to have ...
Variability of Computational Fluid Dynamics Solutions for Pressure and Flow in a Giant Aneurysm: The ASME 2012 Summer Bioengineering Conference CFD Challenge
Publisher: The American Society of Mechanical Engineers (ASME)
Abstract: Stimulated by a recent controversy regarding pressure drops predicted in a giant aneurysm with a proximal stenosis, the present study sought to assess variability in the prediction of pressures and flow by a wide variety ...