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    Controllability Over Wall Thickness of Tubular Structures and Encapsulation During Co-Axial Extrusion of a Thermal-Crosslinking Hydrogel 

    Source: Journal of Manufacturing Science and Engineering:;2020:;volume( 142 ):;issue: 008
    Author(s): Yu, Ilhan; Grindrod, Samantha; Chen, Roland
    Publisher: The American Society of Mechanical Engineers (ASME)
    Abstract: Tubular structures of the hydrogel are used in a variety of applications such as delivering nutrient supplies for 3D cell culturing. The wall thickness of the tube determines the delivery rate. In this study, we used the ...
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    Hydrogel-Forming Microneedle Arrays for Sustained and Controlled Ocular Drug Delivery 

    Source: Journal of Engineering and Science in Medical Diagnostics and Therapy:;2020:;volume( 003 ):;issue: 004:;page 041003-1
    Author(s): Amer, Maher; Chen, Roland K.
    Publisher: The American Society of Mechanical Engineers (ASME)
    Abstract: Microneedles (MNs) provide a minimally invasive alternative to intravitreal injections and a promising means to sustainable ocular drug delivery. To optimize the sustained drug release profile and to ease the administration ...
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    An Experimental Study on Bipolar Tissue Hemostasis and Its Dynamic Impedance 

    Source: Journal of Manufacturing Science and Engineering:;2018:;volume( 140 ):;issue: 006:;page 61016
    Author(s): Li, Xiaoran; Chen, Roland; Li, Wei
    Publisher: The American Society of Mechanical Engineers (ASME)
    Abstract: Bipolar tissue hemostasis is a medical procedure where high frequency alternating current is applied to biological tissue for wound closing and blood vessel sealing through heating. The process is often performed with a ...
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    An Experimental and Numerical Study on Coaxial Extrusion of a Non-Newtonian Hydrogel Material 

    Source: Journal of Manufacturing Science and Engineering:;2021:;volume( 143 ):;issue: 008:;page 081008-1
    Author(s): Yu, Ilhan; Chen, Roland
    Publisher: The American Society of Mechanical Engineers (ASME)
    Abstract: Coaxial extrusion is a commonly used process to manufacture tubular structures to mimic vascular systems in 3D bioprinting. In this study, the stability of coaxial extrusion of a non-Newtonian material, Pluronic F127, is ...
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    Photo-Responsive Hydrogel Microneedles With Interlocking Control for Easy Extraction in Sustained Ocular Drug Delivery 

    Source: Journal of Engineering and Science in Medical Diagnostics and Therapy:;2021:;volume( 005 ):;issue: 001:;page 11001-1
    Author(s): Amer, Maher; Ni, Xiang; Xian, Ming; Chen, Roland K.
    Publisher: The American Society of Mechanical Engineers (ASME)
    Abstract: Microneedle arrays provide a minimally invasive platform for ocular drug delivery. Self-adhesive microneedle arrays, which incorporate barb-like locking features, have been developed to secure the array in place without ...
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    The Effect of Compression Force Uniformity on Bipolar Tissue Welding 

    Source: Journal of Manufacturing Science and Engineering:;2017:;volume( 139 ):;issue: 005:;page 54501
    Author(s): Li, Xiaoran; Borduin, Russel; Chen, Roland K.; Li, Wei
    Publisher: The American Society of Mechanical Engineers (ASME)
    Abstract: Bipolar forceps are a type of electrosurgical device (ESD) widely used for tissue welding in modern surgeries. ESDs have many advantages over traditional surgical tools including reduced blood loss, improved efficiency, ...
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    Characterization of the Electrosurgical Tissue Joining Process Using Dynamic Impedance and Energy Efficiency 

    Source: Journal of Manufacturing Science and Engineering:;2019:;volume( 141 ):;issue: 005:;page 54502
    Author(s): Yang, Che-Hao; Li, Wei; Chen, Roland K.
    Publisher: American Society of Mechanical Engineers (ASME)
    Abstract: Electrosurgical tissue joining is an effective way to create hemostasis, especially in surgical procedures performed in the minimally invasive manner. The quality of tissue joints and potential thermal damages to the ...
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    Dynamic Impedance Monitoring for Large Diameter Vessel Sealing Using Bipolar Electrosurgery 

    Source: Journal of Medical Devices:;2020:;volume( 014 ):;issue: 002
    Author(s): Li, Xiaoran; Li, Wei; Yang, Che-Hao; Chen, Roland K.
    Publisher: The American Society of Mechanical Engineers (ASME)
    Abstract: Vessel sealing using bipolar electrosurgery is becoming a common practice in modern operating rooms. Despite all the advantages such as faster operation, less bleeding, and shorter postsurgery recovery time, side effects ...
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    Biomedical Manufacturing: A Review of the Emerging Research and Applications 

    Source: Journal of Manufacturing Science and Engineering:;2020:;volume( 142 ):;issue: 011:;page 0110807-1
    Author(s): Chen, Roland; Chang, Robert C.; Tai, Bruce; Huang, Yong; Ozdoganlar, Burak; Li, Wei; Shih, Albert
    Publisher: The American Society of Mechanical Engineers (ASME)
    Abstract: Biomedical manufacturing, which has seen rapid growth over the past decade, is an emerging research area for the manufacturing community. This growth trajectory is exemplified and coupled with a broadening scope of ...
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    A Review of State-of-the-Art on Enabling Additive Manufacturing Processes for Precision Medicine 

    Source: Journal of Manufacturing Science and Engineering:;2022:;volume( 145 ):;issue: 001:;page 10802-1
    Author(s): Awad, Atheer; Goyanes, Alvaro; Basit, Abdul W.; Zidan, Ahmed S.; Xu, Changxue; Li, Wei; Narayan, Roger J.; Chen, Roland K.
    Publisher: The American Society of Mechanical Engineers (ASME)
    Abstract: Precision medicine is an emerging healthcare delivery approach that considers variability between patients, such as genetic makeups, in contrast to the current one-size-fits-all approach that is designed to treat the average ...
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