Journal of Medical Devices: Recent submissions
Now showing items 521-540 of 1736
-
Thrombogenicity Testing of Medical Devices in a Minimally Heparinized Ovine Blood Loop
(The American Society of Mechanical Engineers (ASME), 2017)ISO 10993-4 in vivo thrombogenicity testing is frequently performed for regulatory approval of many blood-contacting medical devices and is often a key part of submission packages. Given the current state of in vivo ... -
Finite Element Analysis of the Implantation Process of Overlapping Stents
(The American Society of Mechanical Engineers (ASME), 2017)Overlapping stents are widely used in vascular stent surgeries. However, the rate of stent fractures (SF) and in-stent restenosis (ISR) after using overlapping stents is higher than that of single stent implantations. ... -
Computational Modeling and Comparative Tissue Damage Analysis of Angioplasty and Orbital Atherectomy Interventional Procedures
(The American Society of Mechanical Engineers (ASME), 2017)This research was directed toward quantitatively characterizing the effects of arterial mechanical treatment procedures on the stress and strain energy states of the artery wall. Finite element simulations of percutaneous ... -
Design of a Magnetic Resonance Imaging Guided Magnetically Actuated Steerable Catheter
(The American Society of Mechanical Engineers (ASME), 2017)This paper presents design optimization of a magnetic resonance imaging (MRI) actuated steerable catheter for atrial fibrillation ablation in the left atrium. The catheter prototype, built over polymer tubing, is embedded ... -
Simplified Multistage Computational Approach to Assess the Fatigue Behavior of a Niti Transcatheter Aortic Valve During In Vitro Tests: A Proof-of-Concept Study
(The American Society of Mechanical Engineers (ASME), 2017)Nowadays, transcatheter aortic valve (TAV) replacement is an alternative to surgical therapy in selected high risk patients for the treatment of aortic stenosis. However, left ventricular contraction determines a severe ... -
Computational Modeling of the Mechanical Performance of a Magnesium Stent Undergoing Uniform and Pitting Corrosion in a Remodeling Artery
(The American Society of Mechanical Engineers (ASME), 2017)Coronary stents made from degradable biomaterials such as magnesium alloy are an emerging technology in the treatment of coronary artery disease. Biodegradable stents provide mechanical support to the artery during the ... -
Modeling of Biodegradable Polyesters With Applications to Coronary Stents
(The American Society of Mechanical Engineers (ASME), 2017)The interest in biodegradable polymers for clinical and biomedical engineering applications has seen a dramatic increase in the last 10 years. Recent innovations include bioresorbable polymeric stents (BPS), which are ... -
Statistical Shape Modeling for Cavopulmonary Assist Device Development: Variability of Vascular Graft Geometry and Implications for Hemodynamics
(The American Society of Mechanical Engineers (ASME), 2017)Patients born with a single functional ventricle typically undergo three-staged surgical palliation in the first years of life, with the last stage realizing a cross-like total cavopulmonary connection (TCPC) of superior ... -
Machinability and Optimization of Shrouded Centrifugal Impellers for Implantable Blood Pumps
(The American Society of Mechanical Engineers (ASME), 2017)This paper describes the use of analytical methods to determine machinable centrifugal impeller geometries and the use of computational fluid dynamics (CFD) for predicting the impeller performance. An analytical scheme is ... -
Increased Energy Loss Due to Twist and Offset Buckling of the Total Cavopulmonary Connection
(The American Society of Mechanical Engineers (ASME), 2017)The hemodynamic energy loss through the surgically implanted conduits determines the postoperative cardiac output and exercise capacity following the palliative repair of single-ventricle congenital heart defects. In this ... -
Novel Device For Removal of Blot Clot Obstructions in Drainage Tubes
(The American Society of Mechanical Engineers (ASME), 2017)Medical drains frequently become obstructed requiring removal or re-intervention. Currently, there is no widely accepted practice for maintaining drain patency. A simple device to remove obstructions from medical drains ... -
The Role of Simulation in the Design of a Semi-Enclosed Tubular Embolus Retrieval
(The American Society of Mechanical Engineers (ASME), 2017)A numerical analysis of a semi-enclosed tubular mechanical embolus retrieval device (MERD) for the treatment of acute ischemic stroke (AIS) is presented. In this research, the finite element analysis (FEA) methodology is ... -
Design, Fabrication, and Testing of a Needle-Sized Wrist for Surgical Instruments
(The American Society of Mechanical Engineers (ASME), 2017)This paper presents a miniature wrist that can be integrated into needle-sized surgical instruments. The wrist consists of a nitinol tube with asymmetric cutouts that is actuated by a single tendon to provide high distal ... -
Hemodynamic Profile of Two Aortic Endografts Accounting for Their Postimplantation Position
(The American Society of Mechanical Engineers (ASME), 2017)Endovascular aneurysm repair (EVAR) is a clinically effective technique for treating anatomically eligible abdominal aortic aneurysms (AAAs), involving the deployment of an endograft (EG) that is designed to prevent blood ... -
Innovative Design of an Automatic Acupoint Catgut-Embedding Instrument
(The American Society of Mechanical Engineers (ASME), 2017)Acupoint catgut-embedding (ACE) therapy is a type of acupuncture surgery that combines concepts of traditional Chinese medicine with modern medical instruments. The therapy involves using a hypodermic needle and an acupuncture ... -
Design of a Two Degree-of-Freedom Compliant Tool Tip for a Handheld Powered Surgical Tool
(The American Society of Mechanical Engineers (ASME), 2017)A novel monobloc design of a two degree-of-freedom (DOF) compliant tool tip for a handheld powered surgical tool is presented in this paper. The monobloc tool tip can pitch and yaw using corner-filleted flexure hinge-based ... -
Special Issue: Cardiovascular Device Development and Safety Assessment Using Computational Modeling and Experimental Approaches
(The American Society of Mechanical Engineers (ASME), 2017) -
Design, Analysis, and Optimization of an Acute Stroke Gait Rehabilitation Device
(The American Society of Mechanical Engineers (ASME), 2017)Stroke is one of the leading causes of adult physical disability, and rehabilitation and hospitalization costs for stroke are among the highest for all injuries. Current rehabilitation techniques are labor intensive and ... -
Finite Element Stent Modeling for the Postoperative Analysis of Transcatheter Aortic Valve Implantation
(The American Society of Mechanical Engineers (ASME), 2017)In order to evaluate the performance of stents used in transcatheter aortic valve implantation (TAVI), finite element simulations are setup to reconstruct patient-specific contact forces between implant and its surrounding ... -
Design of Reverse Materials Resurfacing Implants for Mild–Moderate Medial Osteoarthritis of the Knee
(The American Society of Mechanical Engineers (ASME), 2017)The areas of the most frequent cartilage loss in mild–moderate medial osteoarthritis (OA) were reviewed from previous studies. Implant components were designed to resurface these areas. The surface geometries of the ...