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dc.contributor.authorPinto Costa, Rayanne
dc.contributor.authorNwotchouang, Blaise Simplice Talla
dc.contributor.authorYao, Junyao
dc.contributor.authorBiswas, Dipankar
dc.contributor.authorCasey, David
dc.contributor.authorMcKenzie, Ruel
dc.contributor.authorSebastian, Frederick
dc.contributor.authorAmini, Rouzbeh
dc.contributor.authorSteinman, David A.
dc.contributor.authorLoth, Francis
dc.date.accessioned2023-11-29T18:39:34Z
dc.date.available2023-11-29T18:39:34Z
dc.date.copyright12/5/2022 12:00:00 AM
dc.date.issued12/5/2022 12:00:00 AM
dc.date.issued2022-12-05
dc.identifier.issn0148-0731
dc.identifier.otherbio_145_04_041001.pdf
dc.identifier.urihttp://yetl.yabesh.ir/yetl1/handle/yetl/4294300
dc.description.abstractPrevious experimental flow studies have demonstrated a delay (∼20%) in transition to turbulence for whole blood compared to a Newtonian analog fluid in both a straight pipe and eccentric stenosis model with ridged walls. The impact of wall compliance on the transition to turbulence of blood compared to Newtonian analog and on wall vibration is unknown. The present study employed flexible walls downstream of an eccentric stenosis model and examined the wall vibration during the transition to turbulence with whole blood and a Newtonian analog. Measurements of tube wall vibration velocity (WVV) were used as an indicator of the turbulence level within the flexible tube. WVV was measured at 5, 10, and 15 diameters downstream of the stenosis using a laser Doppler vibrometer at Reynolds numbers 0, 200, 300, 350, 400, 450, 500, 550, 600, 650, 700, and 750. The root mean squares (RMS) of the measured WVV were utilized as an indirect measure of fluid velocity fluctuations present at that location, and hence, an indicator of transition to turbulence. WVV RMS was near-constant until approximately Reynolds number 400. It increased monotonically with Reynolds number for both whole blood and the Newtonian fluid. No differences in the transition to turbulence were observed between whole blood and the Newtonian fluid, as the WVV RMS curves were remarkably similar in shape. This result suggests that rheology had minimal impact on the WVV downstream of a stenosis for transition to turbulence since the fluids had a similar level of vibration.
dc.publisherThe American Society of Mechanical Engineers (ASME)
dc.titleImpact of Blood Rheology on Transition to Turbulence and Wall Vibration Downstream of a Stenosis
dc.typeJournal Paper
dc.journal.volume145
dc.journal.issue4
dc.journal.titleJournal of Biomechanical Engineering
dc.identifier.doi10.1115/1.4055856
dc.journal.fristpage41001-1
dc.journal.lastpage41001-9
dc.page9
dc.treeJournal of Biomechanical Engineering:;2022:;volume( 145 ):;issue: 004
dc.contenttypeFulltext


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