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contributor authorKo, Kwang Bem
contributor authorSeo, Jung-Hee
contributor authorDoshi, Ashish
contributor authorSen, Danielle Gottlieb
contributor authorMittal, Rajat
date accessioned2024-12-24T18:41:12Z
date available2024-12-24T18:41:12Z
date copyright9/6/2024 12:00:00 AM
date issued2024
identifier issn0148-0731
identifier otherbio_146_12_121002.pdf
identifier urihttp://yetl.yabesh.ir/yetl1/handle/yetl/4302560
description abstractPulmonary valves do not display a fibrous annulus as do other valves in the heart; thus, pulmonary valves can be implanted at multiple orientations and locations within the right ventricular outflow tract (RVOT). This gives surgeons more freedom when implanting the valve but it also results in uncertainties regarding placement, particularly with respect to valve orientation. We investigate the pulmonary artery hemodynamics and valve leaflet dynamics of pulmonary valve replacements (PVRs) with various orientations via fluid–structure interaction (FSI) models. A canonical model of the branching pulmonary artery is coupled with a dynamic model of a pulmonary valve, and from this we quantify the effect of valve implant orientation on the postvalvular hemodynamics and leaflet dynamics. Metrics such as turbulent kinetic energy (TKE), branch pulmonary artery flow distributions, projected valve opening area (PVOA), and pressure differentials across the valve leaflets are analyzed. Our results indicate that off-axis orientation results in higher pressure forces and flow and energy asymmetry, which potentially have implications for long-term durability of implanted bioprosthetic valves.
publisherThe American Society of Mechanical Engineers (ASME)
titleComputational Study on the Effects of Valve Orientation on the Hemodynamics and Leaflet Dynamics of Bioprosthetic Pulmonary Valves
typeJournal Paper
journal volume146
journal issue12
journal titleJournal of Biomechanical Engineering
identifier doi10.1115/1.4066178
journal fristpage121002-1
journal lastpage121002-12
page12
treeJournal of Biomechanical Engineering:;2024:;volume( 146 ):;issue: 012
contenttypeFulltext


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