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contributor authorSingh, Anita
contributor authorMagee, Rachel
contributor authorBalasubramanian, Sriram
date accessioned2022-02-06T05:40:45Z
date available2022-02-06T05:40:45Z
date copyright7/14/2021 12:00:00 AM
date issued2021
identifier issn0148-0731
identifier otherbio_143_11_114501.pdf
identifier urihttp://yetl.yabesh.ir/yetl1/handle/yetl/4278530
description abstractDespite occurrence of neonatal hypoxia and peripheral nerve injuries in complicated birthing scenarios, the effect of hypoxia on the biomechanical responses of neonatal peripheral nerves is not studied. In this study, neonatal brachial plexus (BP) and tibial nerves, obtained from eight normal and eight hypoxic 3–5-day-old piglets, were tested in uniaxial tension until failure at a rate of 0.01 mm/s or 10 mm/s. Failure load, stress, and modulus of elasticity were reported to be significantly lower in hypoxic neonatal BP and tibial nerves than respective normal tissue at both 0.01 and 10 mm/s rates. Failure strain was significantly lower in the hypoxic neonatal BP nerves only at 10 mm/s rate when compared to normal BP nerve. This is the first available data that indicate weaker mechanical behavior of hypoxic neonatal peripheral nerves as compared to normal tissue and offer an understanding of the biomechanical responses of peripheral nerves of hypoxic neonatal piglets.
publisherThe American Society of Mechanical Engineers (ASME)
titleAn In Vitro Study to Investigate Biomechanical Responses of Peripheral Nerves in Hypoxic Neonatal Piglets
typeJournal Paper
journal volume143
journal issue11
journal titleJournal of Biomechanical Engineering
identifier doi10.1115/1.4051283
journal fristpage0114501-1
journal lastpage0114501-4
page4
treeJournal of Biomechanical Engineering:;2021:;volume( 143 ):;issue: 011
contenttypeFulltext


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