| contributor author | Bertram, C. D. | |
| contributor author | Macaskill, C. | |
| contributor author | Moore, Jr., J. E. | |
| date accessioned | 2019-09-18T09:01:47Z | |
| date available | 2019-09-18T09:01:47Z | |
| date copyright | 7/30/2019 12:00:00 AM | |
| date issued | 2019 | |
| identifier issn | 0148-0731 | |
| identifier other | bio_141_11_111006 | |
| identifier uri | http://yetl.yabesh.ir/yetl1/handle/yetl/4258039 | |
| description abstract | The phasic contractions of collecting lymphatic vessels are reduced in strength and occur at diminished frequency when a favorable pressure difference and the resulting antegrade flow create large fluid shear stresses at the luminal surface. This paper describes a minimal phenomenological model of this mechanism that is applied to a previously validated numerical model of a phasically contracting lymphangion. The parameters of the inhibition model are quantitatively matched to observations in isolated segments of rat lymphatic vessel, first for mesenteric lymphatics then for thoracic duct, and outcomes from the numerical model are then qualitatively compared with recent observations in isolated segments of rat thoracic duct. | |
| publisher | American Society of Mechanical Engineers (ASME) | |
| title | Inhibition of Contraction Strength and Frequency by Wall Shear Stress in a Single-Lymphangion Model | |
| type | Journal Paper | |
| journal volume | 141 | |
| journal issue | 11 | |
| journal title | Journal of Biomechanical Engineering | |
| identifier doi | 10.1115/1.4043724 | |
| journal fristpage | 111006 | |
| journal lastpage | 111006-8 | |
| tree | Journal of Biomechanical Engineering:;2019:;volume( 141 ):;issue: 011 | |
| contenttype | Fulltext | |
