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contributor authorXie, Wanchuan
contributor authorLewis, Weston M.
contributor authorKaser, Jared
contributor authorRoss Welch, C.
contributor authorLi, Pengbo
contributor authorNelson, Carl A.
contributor authorKothari, Vishal
contributor authorTerry, Benjamin S.
date accessioned2017-11-25T07:19:49Z
date available2017-11-25T07:19:49Z
date copyright2017/7/6
date issued2017
identifier issn0148-0731
identifier otherbio_139_08_081003.pdf
identifier urihttp://138.201.223.254:8080/yetl1/handle/yetl/4236030
description abstractWe have proposed a long-term, noninvasive, nonrestrictive method of delivering and implanting a biosensor within the body via a swallowable implantation capsule robot (ICR). The design and preliminary validation of the ICR’s primary subsystem—the sensor deployment system—is discussed and evidence is provided for major design choices. The purpose of the sensor deployment system is to adhere a small biosensor to the mucosa of the intestine long-term, and the modality was inspired by tapeworms and other organisms that employ a strategy of mechanical adhesion to soft tissue via the combined use of hooks or needles and suckers. Testing was performed to refine the design of the suction and needle attachment as well as the sensor ejection features of the ICR. An experiment was conducted in which needle sharpness, needle length, and vacuum volume were varied, and no statistically significant difference was observed. Finally, preliminary testing, coupled with prior work within a live porcine model, provided evidence that this is a promising approach for implanting a biosensor within the small intestine.
publisherThe American Society of Mechanical Engineers (ASME)
titleDesign and Validation of a Biosensor Implantation Capsule Robot
typeJournal Paper
journal volume139
journal issue8
journal titleJournal of Biomechanical Engineering
identifier doi10.1115/1.4036607
journal fristpage81003
journal lastpage081003-10
treeJournal of Biomechanical Engineering:;2017:;volume( 139 ):;issue: 008
contenttypeFulltext


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