| contributor author | Manolidis, Michail | |
| contributor author | Isabey, Daniel | |
| contributor author | Louis, Bruno | |
| contributor author | Grotberg, James B. | |
| contributor author | Filoche, Marcel | |
| date accessioned | 2017-11-25T07:18:00Z | |
| date available | 2017-11-25T07:18:00Z | |
| date copyright | 2016/11/03 | |
| date issued | 2016 | |
| identifier issn | 0148-0731 | |
| identifier other | bio_138_12_121005.pdf | |
| identifier uri | http://138.201.223.254:8080/yetl1/handle/yetl/4234897 | |
| description abstract | The mucociliary clearance in the bronchial tree is the main mechanism by which the lungs clear themselves of deposited particulate matter. In this work, a macroscopic model of the clearance mechanism is proposed. Lubrication theory is applied for thin films with both surface tension effects and a moving wall boundary. The flow field is computed by the use of a finite-volume scheme on an unstructured grid that replicates a bronchial bifurcation. The carina in bronchial bifurcations is of special interest because it is a location of increased deposition of inhaled particles. In this study, the mucus flow is computed for different values of the surface tension. It is found that a minimal surface tension is necessary for efficiently removing the mucus while maintaining the mucus film thickness at physiological levels. | |
| publisher | The American Society of Mechanical Engineers (ASME) | |
| title | A Macroscopic Model for Simulating the Mucociliary Clearance in a Bronchial Bifurcation: The Role of Surface Tension | |
| type | Journal Paper | |
| journal volume | 138 | |
| journal issue | 12 | |
| journal title | Journal of Biomechanical Engineering | |
| identifier doi | 10.1115/1.4034507 | |
| journal fristpage | 121005 | |
| journal lastpage | 121005-8 | |
| tree | Journal of Biomechanical Engineering:;2016:;volume( 138 ):;issue: 012 | |
| contenttype | Fulltext | |
