| contributor author | Chen, Joseph | |
| contributor author | Peacock, Jon R. | |
| contributor author | Branch, Janelle | |
| contributor author | David Merryman, W. | |
| date accessioned | 2017-05-09T01:15:00Z | |
| date available | 2017-05-09T01:15:00Z | |
| date issued | 2015 | |
| identifier issn | 0148-0731 | |
| identifier other | bio_137_02_020903.pdf | |
| identifier uri | http://yetl.yabesh.ir/yetl/handle/yetl/157070 | |
| description abstract | Calcific aortic valve disease (CAVD) is a significant cardiovascular disorder characterized by the formation of calcific nodules (CN) on the valve. In vitro assays studying the formation of these nodules were developed and have led to many significant mechanistic findings; however, the biophysical properties of CNs have not been clearly defined. A thorough analysis of dystrophic and osteogenic nodules utilizing scanning electron microscopy (SEM), energy dispersive spectrometry (EDS), and atomic force microscopy (AFM) was conducted to describe calcific nodule properties and provide a link between calcific nodule morphogenesis in vitro and in vivo. Unique nodule properties were observed for dystrophic and osteogenic nodules, highlighting the distinct mechanisms occurring in valvular calcification. | |
| publisher | The American Society of Mechanical Engineers (ASME) | |
| title | Biophysical Analysis of Dystrophic and Osteogenic Models of Valvular Calcification | |
| type | Journal Paper | |
| journal volume | 137 | |
| journal issue | 2 | |
| journal title | Journal of Biomechanical Engineering | |
| identifier doi | 10.1115/1.4029115 | |
| journal fristpage | 20903 | |
| journal lastpage | 20903 | |
| identifier eissn | 1528-8951 | |
| tree | Journal of Biomechanical Engineering:;2015:;volume( 137 ):;issue: 002 | |
| contenttype | Fulltext | |
