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contributor authorQiao, Aike
contributor authorZhang, Zhanzhu
date accessioned2017-05-09T01:05:23Z
date available2017-05-09T01:05:23Z
date issued2014
identifier issn0148-0731
identifier otherbio_136_04_041007.pdf
identifier urihttp://yetl.yabesh.ir/yetl/handle/yetl/153993
description abstractWe sought to investigate the effects of endovascular stents with different links for treating stenotic vertebral artery and to determine the relationship between the shape of the link and instent restenosis (ISR). We also attempted to provide scientific guidelines for stent design and selection for clinical procedures. Models of three types of stent with different links (Lstent, Vstent, and Sstent) and an idealized stenotic vertebral artery were established. The deployment procedure for the stent in the stenotic vertebral artery was simulated for solid mechanics analysis. Next, the deformed models were extracted to construct the blood flow domain, and numerical simulations of the hemodynamics in these models were performed using the finite element method. The numerical results demonstrated that: (1) Compared with the Lstent and Vstent, the Sstent has a better flexibility and induces less stress in the stent strut. Furthermore, less stress is generated in the arterial wall. (2) Vascular straightening is scarcely influenced by the shape of the link, but it is closely related to the flexibility of the stent. (3) The Sstent has the smallest foreshortening among the three types of stents. (4) Compared with the Vstent and Sstent, the Lstent causes a smaller area with low wall shear stress, less blood stagnation area, and better blood flow close to the artery wall. From the viewpoint of the combination of solid mechanics and hemodynamics, the Sstent has better therapeutic effects because of its lower potential for inducing ISR and its better prospects in clinical applications compared with the Lstent and Vstent.
publisherThe American Society of Mechanical Engineers (ASME)
titleNumerical Simulation of Vertebral Artery Stenosis Treated With Different Stents
typeJournal Paper
journal volume136
journal issue4
journal titleJournal of Biomechanical Engineering
identifier doi10.1115/1.4026229
journal fristpage41007
journal lastpage41007
identifier eissn1528-8951
treeJournal of Biomechanical Engineering:;2014:;volume( 136 ):;issue: 004
contenttypeFulltext


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