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contributor authorAlexander H. Slocum
contributor authorAnand Jagannath
contributor authorTyrel Waagen
contributor authorArvind K. Agnihotri
contributor authorRobert A. Levine
date accessioned2017-05-09T00:46:12Z
date available2017-05-09T00:46:12Z
date copyrightJune, 2011
date issued2011
identifier issn1932-6181
identifier otherJMDOA4-28018#027521_1.pdf
identifier urihttp://yetl.yabesh.ir/yetl/handle/yetl/147239
description abstractPercutaneous treatments for heart disease have created new challenges for both physicians and medical device developers and manufacturers. In order to deliver the highest-quality care to patients, developers and physicians must be able to more easily access the intracardiac environment during the initial phases of device development and while learning to implement new tools and methods. We have developed a pulsatile flow model (PFM), which simulates the intracardiac environment using a bellows-pump and closed fluid flow circuit. The PFM is also outfitted with video imaging and other sensors to provide real-time feedback to a user. The PFM was used to aid in the development of a catheter for the percutaneous treatment of mitral regurgitation via chordal cutting. Knowledge gained from tests with the PFM are now being used by a manufacturer to produce catheters, which would be appropriate for more in-depth trials in both animal and human models. The pulsatile flow model provide physicians and manufacturers of cardiac surgical devices a platform for increasing the efficiency of the development process as well as the physicians ability to better treat patients.
publisherThe American Society of Mechanical Engineers (ASME)
titleA Pulsatile-Flow Model for Intracardiac Surgical Device Development
typeJournal Paper
journal volume5
journal issue2
journal titleJournal of Medical Devices
identifier doi10.1115/1.3590584
journal fristpage27521
identifier eissn1932-619X
keywordsPulsatile flow
treeJournal of Medical Devices:;2011:;volume( 005 ):;issue: 002
contenttypeFulltext


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